Endogenous antibody response to SARS-CoV-2 in patients who received monoclonal antibodies against COVID-19: A systematic review

Andrea Lombardi , Cecilia Azzarà , Giulia Renisi , Giulia Viero , Andrea Gori , Alessandra Bandera
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引用次数: 1

Abstract

Passive immunization with mAbs has been employed in COVID-19. We performed a systematic review of the literature assessing the endogenous humoral immune response against SARS-CoV-2 in patients treated with mAbs. Administration of mAbs in seronegative patients led to a reduction in both antibody titres and neutralizing activity against the virus.

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接受COVID-19单克隆抗体的患者对SARS-CoV-2的内源性抗体反应:一项系统综述
单克隆抗体被动免疫已应用于COVID-19。我们进行了一项系统的文献综述,评估了单克隆抗体治疗患者对SARS-CoV-2的内源性体液免疫反应。在血清阴性患者中使用单克隆抗体导致抗体滴度和对病毒的中和活性降低。
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