Model-Based Re-Design of some Genetic Regulatory Circuits to get Genetic Modified Micro-organisms (GMO) by using Engineering Computational Tools

G. Maria
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Abstract

The paper is aiming at reviewing the main math modelling and computational tools developed by Maria (2017,2018) [1-3] to in-silico re-design genetic regulation circuits (GRC) in living cells to get GMOs of desired characteristics. A number of suggestive examples (case studies) are mentioned as well.
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利用工程计算工具对基因调控回路进行基于模型的再设计以获得转基因微生物
本文旨在回顾Maria(2017,2018)[1-3]开发的主要数学建模和计算工具,用于在活细胞中重新设计遗传调控电路(GRC),以获得所需特性的转基因生物。书中还提到了一些具有启发性的例子(案例研究)。
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