Studying the Immune Profile and Susceptibility to Microbial Infections in Obese Adults

Mohammad A. K. Al-Saadi, H. Farhood, F. Al-Zayadi
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Abstract

Objectives: This study aims at studying the effect of adult obesity on immunologic profile and IFN- γ was not significant decreased in obese group, while concentrations of C3 & C4 were a highly significant increased (p ˂ 0.001) in obese group, phagocytic index was a highly significant decreased in obese subjects (p ˂ 0.001). Regarding the susceptibility to microbial infections the concentrations of ASO & anti-measles virus IgG in obese group were a highly significant more than controls. Conclusions: This result may provide clear evidence that obese subjects are more susceptible to microbial infections than normal subjects.
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研究肥胖成人的免疫特征和对微生物感染的敏感性
目的:本研究旨在研究成人肥胖对免疫特性的影响,肥胖组IFN- γ无显著降低,而肥胖组C3和C4浓度显著升高(p小于0.001),肥胖组吞噬指数显著降低(p小于0.001)。在对微生物感染的敏感性方面,肥胖组ASO和抗麻疹病毒IgG浓度显著高于对照组。结论:本研究结果为肥胖者比正常人更易发生微生物感染提供了明确的证据。
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