Sintesis dan pencirian terbitan biskumarin dan benzopirano dikumarin

Abstract

The wide-ranging biological activities of 4-hydroxycoumarin have stimulated considerable interest in this class of compounds, and various biscoumarin derivatives have been synthesized. Recently, a number of methods have been reported for the synthesis of biscoumarin by the reaction of 4-hydroxycoumarin and various aldehydes in the presence of catalysts. In the present study, a new series of biscoumarin and benzopyrano dicoumarin were synthesized and physically characterized by nuclear magnetic resonane (H and C NMR), fourier transform infrared spectroscopy (FTIR), mass spectrometry (MS) and melting point.