POLYPHENOLS AS PROTECTIVE AGENTS AGAINST NEUROTOXICITY AND NEURODEGENERATION: THE CASE OF TEA POLYPHENOLS

M. Alves, S. Almeida, A. R. Nunes, M. Sousa, P. Moreira, P. Oliveira, B. Silva
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Abstract

Europe has the highest proportion of older persons in the World. As population ages, it is imperative to find new strategies to avoid or counteract the effects of the incurable neurodegenerative diseases, which already represent a great financial and emotional burden for health care systems, patients, and their families. In this talk, Branca Silva (PhD) will discuss whether polyphenols obtained from diet or food supplements constitute an effective and low-cost strategy to prevent or treat neurodegeneration and neurotoxicity. Special focus will be given to the recent works of her research team about the beneficial effects to the brain of the regular consumption of white tea (Camellia sincensis L.) and its polyphenols. She will also highlight the safety, mechanisms of action, and the current and future relevance of polyphenols in the prevention and therapy of neurodegenerative disorders.
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茶多酚作为神经毒性和神经变性的保护剂:以茶多酚为例
欧洲是世界上老年人比例最高的国家。随着人口老龄化,必须找到新的策略来避免或抵消无法治愈的神经退行性疾病的影响,这些疾病已经给卫生保健系统、患者及其家庭带来了巨大的经济和情感负担。在这次演讲中,布兰卡·席尔瓦博士将讨论从饮食或食品补充剂中获得的多酚是否构成一种有效和低成本的策略,以预防或治疗神经变性和神经毒性。她的研究小组最近的工作将特别关注经常饮用白茶(Camellia sincensis L.)及其多酚对大脑的有益作用。她还将强调多酚在预防和治疗神经退行性疾病中的安全性、作用机制以及当前和未来的相关性。
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