Genome-wide analysis of PHD-finger protein family in Arabidopsis thaliana.

Zhang Fan, Y. Zhongnan, Z. Sen
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引用次数: 6

Abstract

PHD-finger proteins were found universally in eukaryotes and known as key players in regulating chromatin or transcription.In animals,many PHD-finger proteins had been well studied on structure and function.Compared to animals,only a few of plant PHD-finger proteins had been characterized functionally.By both SMART and Pfam searches,70 members of the PHD-finger family were identified in Arabidopsis thaliana.Most of the PHD-finger proteins in Arabidopsis thaliana were functionally unknown.A complete overview of this family by bioinformatic approach were presented in this paper,including the gene structure,gene localization in genome,gene expression,protein motif organization,and phylogenetic relationship of each family member.These results should provide useful information for the further structural and functional studies of PHD-finger proteins.
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拟南芥博士指蛋白家族的全基因组分析。
博士指蛋白普遍存在于真核生物中,被认为是调节染色质或转录的关键角色。在动物中,许多博士指蛋白的结构和功能已经得到了很好的研究。与动物相比,只有少数植物博士指蛋白被功能表征。通过SMART和Pfam搜索,在拟南芥中确定了70个博士手指家族成员。拟南芥中大部分PHD-finger蛋白的功能未知。本文利用生物信息学方法对该家族的基因结构、基因组定位、基因表达、蛋白基序组织以及各家族成员的系统发育关系等方面进行了综述。这些结果将为进一步研究博士指蛋白的结构和功能提供有用的信息。
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