Review on Spatial Memory, Psychosis and Cognitive Dysfunction Screening Methods in Rat models

Abhishek Yekkaladev, Koppala Rvs Chaitanya
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Abstract

Assessment of memory and learning in animal models has been extensively employed in scientific research. Among many disorders,inthis article, we emphasise anoverall review of memory-related problems like those representing diseases with primary processes of affected memory –such as amnesia, dementia, brain ageing, neurodevelopment, trauma, epilepsy and neuropsychiatric disorders, etc. Toxic effects of specific drugs and other exploring are often responsible for these conditions. There is a diversification of experimental methods assessing animal learning and memory skills. We have many memories assessment models today to test memory along with maze in rodents; there are also other several types of them, but their real usefulness, advantages and applications stay to be completely settled and rely upon the specific variation chosenby the experimenter. The point of the current article is first, to momentarily audit the collected information concerning spatial memory tasks; second, to welcome the reader data on the various types of memory diseases in rodents; and third, to elucidate the usefulness and limitations of different available plant sources to treat memory and learning disorders.
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空间记忆、精神病和认知功能障碍大鼠模型筛选方法综述
动物模型的记忆和学习评估已广泛应用于科学研究。在这篇文章中,我们强调了对记忆相关问题的全面回顾,比如那些代表着受影响记忆的主要过程的疾病,如健忘症、痴呆、脑老化、神经发育、创伤、癫痫和神经精神疾病等。特定药物的毒性作用和其他探索通常是造成这些情况的原因。评估动物学习和记忆技能的实验方法多种多样。我们现在有很多记忆评估模型来测试啮齿动物的记忆迷宫;还有其他几种类型,但它们的真正用途、优点和应用还有待完全解决,并取决于实验者选择的具体变化。本文的重点是,首先,对收集到的空间记忆任务信息进行暂时审计;第二,欢迎读者对各类啮齿动物记忆疾病的资料;第三,阐明不同可用植物来源治疗记忆和学习障碍的有效性和局限性。
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