Evaluation of Clinical Presentation and Associated Comorbid Conditions in Patients with Spontaneous Intracerebral Hemorrhage in a Tertiary Care Hospital in Bangladesh

Richmond Ronald Gomes, Shoriful Islam, FM Monjur Hasan
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Abstract

Spontaneous intracerebral hemorrhage (ICH) has remained the least treatable form of stroke despite recent improvements in medical treatment. Treatment usually supportive and medical such as ventilatory support, blood pressure reduction, osmotherapy, fever control, seizure control and nutritional support and treatment of co morbidconditions. This study was carried out to see demographic variability, clinical presentation, causes and outcome of spontaneous intracerebral hemorrhage. Methods and materials: This was a cross sectional observational prospective in study on 50 spontaneous ICH patients admitted in Medicine department of Khulna Medical College Hospital from November 2020 to April, 2021. Result: The study showed that spontaneous ICH was most common in between 41-70 years. Their age frequency were 14 (28%) in 41-50 years, 15 (30%)in 51- 60 years, 12 (24%) in 61-70 years, 5 (10%) in 71- 80 years and 4 (8%) in more than 81 years age group. Among the patients, 64% (32) were male and 36% (18) were female. No of smoker male was 25(50%) and female was 1(2%) and no of nonsmoker male was 7(14%) and female was 17(34%). Headache was present in 56% (28) and absent in 44% (22) of patients. Vomiting was present in 54% (27) and was absent in 46% (23)of patients.Seizure was present in 16% (8) and was absent in 54% (42) of patients. Diabetes mellitus was present in 22% (11) of patients and absent in 78% (39) patients. Range of blood pressure –<140/90 in 24%(12), Systolic BP:140-159/Diastolic BP:90-99 (mm Hg) in 10%(5), Systolic BP:160-179/Diastolic BP:100-109 (mm Hg) in 22%(11),Systolic BP:180 or more/Diastolic BP:110 or more (mm Hg) in 44%(22) patients. Dyslipidemia was present in 30% (15) & absent in 70% (35) patients. Glasgow Coma Scale Score was 8 or less in 42% (21) and 9 or more in 58% (29) patients. Conclusion: Spontaneous ICH is common in Indian subcontinent. As death occur due to ICH itself, associated co morbidities or due to complications, management in stroke care unit, High dependency unit and Intensive care unit is required.
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孟加拉国一家三级医院自发性脑出血患者的临床表现和相关合并症的评估
自发性脑出血(ICH)仍然是最难治疗的形式的中风,尽管最近的医学治疗的改进。治疗通常为支持和医疗,如呼吸机支持、降血压、渗透疗法、发热控制、癫痫控制和营养支持以及对合并症的治疗。本研究旨在了解自发性脑出血的人口学变异、临床表现、病因和预后。方法与材料:对2020年11月至2021年4月库尔纳医学院附属医院内科收治的50例自发性脑出血患者进行横断面观察前瞻性研究。结果:自发性脑出血多见于41 ~ 70岁年龄组。41 ~ 50岁14例(28%),51 ~ 60岁15例(30%),61 ~ 70岁12例(24%),71 ~ 80岁5例(10%),81岁以上4例(8%)。其中男性32例,占64%,女性18例,占36%。吸烟男性25人(50%),女性1人(2%);不吸烟男性7人(14%),女性17人(34%)。56%(28)的患者出现头痛,44%(22)的患者没有头痛。54%(27)的患者出现呕吐,46%(23)的患者无呕吐。16%(8)的患者出现癫痫发作,54%(42)的患者没有癫痫发作。22%(11例)患者存在糖尿病,78%(39例)患者无糖尿病。24%(12)患者血压<140/90,10%(5)患者收缩压:140-159/舒张压:90-99 (mm Hg), 22%(11)患者收缩压:160-179/舒张压:100-109 (mm Hg), 44%(22)患者收缩压:180及以上/舒张压:110及以上(mm Hg)。30%(15)例患者存在血脂异常,70%(35)例患者无血脂异常。42%(21人)的格拉斯哥昏迷评分低于或等于8分,58%(29人)的格拉斯哥昏迷评分高于或等于9分。结论:自发性脑出血在印度次大陆较为常见。由于脑出血本身、相关合并症或并发症导致死亡,需要在卒中护理病房、高度依赖病房和重症监护病房进行管理。
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