Evaluation of Erectile Function and Mood Changes among Male Patients with Hansen's disease

A. Moussa, Hany H. Dessoki, G. Ahmed, M. Farag
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Abstract

Purpose: To evaluate evaluation of the erectile function and mood changes in male patients with Hansen’s disease (HD). Methods: this study was conducted on fForty males (40) confirmed patients with Hansen's disease were enrolled in this research., theAll patients were subjected to the underwent the following: full Hhistory taking, International index of erectile function (IIEF-5), Beck anxiety scale and Beck depression scale. Results: About 77.5% of our patients had erectile dysfunction, and 87.5% of patients showed anxiety disorders. while While 52.5% of patients showed depressive disorders and, 27.5% of patients had abnormal free testosterone levels. There was A high negative significant correlation revealed between IIEF-5 score and deformity grading, but with there was no significant association between duration or type of leprosy and psychiatric disorders. The results showed significant negative correlation between IIEF-5 and Beck depression inventory. But no statistical significant difference regarding free testosterone level (p-value=0.109) was found between erectile dysfunction (ED) group and non ED group. Conclusion: Erectile dysfunction, anxiety and depression are very common in among patients with Hansen's disease. and sSuch problems are related to level of deformity not to type or duration of disease and not related to testosterone level. This finding could be of key importance for the clinical practice because it could modify the current management of patients with Hansen's disease.
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男性汉森病患者勃起功能和情绪变化的评价
目的:评价男性汉森病(HD)患者的勃起功能和情绪变化。方法:本研究纳入40例确诊的汉森病男性患者(40例)。所有患者均接受完整病史调查、国际勃起功能指数(IIEF-5)、Beck焦虑量表和Beck抑郁量表。结果:77.5%的患者存在勃起功能障碍,87.5%的患者存在焦虑障碍。52.5%的患者表现出抑郁障碍,27.5%的患者游离睾酮水平异常。IIEF-5评分与畸形分级呈高度负显著相关,但麻风病病程或类型与精神障碍无显著相关性。结果显示IIEF-5与Beck抑郁量表呈显著负相关。勃起功能障碍(ED)组与非ED组游离睾酮水平差异无统计学意义(p值=0.109)。结论:汉森病患者普遍存在勃起功能障碍、焦虑、抑郁等症状。这些问题与畸形程度有关,与疾病的类型或持续时间无关,也与睾丸激素水平无关。这一发现可能对临床实践至关重要,因为它可以改变目前对汉森氏病患者的管理。
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