POTENSI EKSTRAK POLISAKARIDA LARUT AIR (PLA) DARI BIJI ASAM (Tamarindus indica L) SEBAGAI KONTROL BERAT BADAN DAN GLUKOSA DARAH

Harijono Harijono, Aulia Azizah Syamsuri, K. Fibrianto, Siti Narsito Wulan, Hera Sisca Prasmita
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Abstract

Tamarind seed (Tamarindus indica L) is one of Indonesian’s local potentials, especially in Nusa Tenggara. Water-soluble polysaccharides (PLA) of Tamarind seeds act as a source of fiber that controls weight and blood glucose level. The aim of this research is to optimize extraction of Water-soluble polysaccharides (PLA) from Tamarind seeds that have best yield and solubility as a control of weight and glucose levels. The optimized used Box Behnken Design (BBD) at Design Expert 10.0 software. The optimal result was verified and tested as a weight and blood glucose levels controller. The result shows that the intake of water-soluble polysaccharides from Tamarind seeds during 40 days was significant in glucose levels of rats. The conclusion of this research was water-soluble polysaccharides from the crude extract of tamarind seeds could reduce glucose levels of high-fat diet rats.
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罗望子(Tamarindus indica L)是印度尼西亚的地方潜力之一,特别是在努沙登加拉。罗望子的水溶性多糖(PLA)作为纤维的来源,控制体重和血糖水平。本研究的目的是优化罗望子中水溶性多糖(PLA)的提取工艺,使其在控制体重和血糖水平的条件下具有最佳的产率和溶解度。优化使用Box Behnken Design (BBD)在Design Expert 10.0软件。验证了最佳结果,并作为体重和血糖水平控制器进行了测试。结果表明,40 d内摄入罗望子水溶性多糖对大鼠血糖水平有显著影响。结论罗望子粗提物水溶性多糖具有降低高脂饮食大鼠血糖水平的作用。
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