Ethnopharmacological and Phytochemical Studies of Tridax Procumbens Linn: A Popular Herb in Ayurveda Medicine

Dewashish Kaushik, Alokit Tanwar, Joseph B. Davis
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引用次数: 2

Abstract

Tridax procumbens (T. procumbens) Linn. is a medicinal plant found in tropical, sub-tropical and mild temperate regions around the world being used in Ayurveda treatment for liver disorders, boils, blisters, cuts, wound healing and as an anticoagulant, antifungal, and insect repellent. The plant is known to contain flavonoids, alkaloids, carotenoids, hydroxycinnamates, lignans, benzoic acid derivatives, phytosterols and tannins. The plant is also associated with endophytes to produce secondary metabolies by endophytes possessing antibacterial and antifungal activities. Different parts of this plant and essential oil are associated with ethnopharmacological properties like wound healing, antibacterial, immunomodulation, antiinflammatory, antidiabetic, vasorelaxant, antihyperlipidemic, anticancer, antiplasmodial, anticoagulation and antihepatic. Most of these studies validate the concept of earlier claims that T. procumbens’s potential as a medicinal plant. Further studies are required to unravel other pharmacological activities as well as the target-based mechanism of actions. The review also highlights the need for exploring lead molecules from these myriad of compounds that are of vital importance in drug discovery strategies.
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阿育吠陀医学中常用草药三叶草的民族药理学和植物化学研究
原丘姆草(t.p ocumbens)是一种药用植物,生长在世界各地的热带、亚热带和温和温带地区,被用于阿育吠陀治疗肝脏疾病、疖子、水泡、割伤、伤口愈合,并作为抗凝血剂、抗真菌剂和驱虫剂。已知这种植物含有黄酮类、生物碱、类胡萝卜素、羟基肉桂酸、木脂素、苯甲酸衍生物、植物甾醇和单宁。该植物还与内生菌相关,通过具有抗菌和抗真菌活性的内生菌产生次生代谢。这种植物和精油的不同部分与民族药理学特性有关,如伤口愈合、抗菌、免疫调节、抗炎、降糖、血管松弛、抗高脂血症、抗癌、抗疟原虫、抗凝血和抗肝脏。这些研究大多证实了早期的概念,即原春草作为一种药用植物的潜力。需要进一步的研究来揭示其他药理活性以及基于靶点的作用机制。该综述还强调了从这些无数化合物中探索铅分子的必要性,这些化合物对药物发现策略至关重要。
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