Bioactive Curcumin and its Effects on Lowering Systemic Inflammation as Measured by CRP: A Systematic Review

IF 0.5 Q4 HEALTH CARE SCIENCES & SERVICES Internet Journal of Allied Health Sciences and Practice Pub Date : 2022-06-29 DOI:10.46743/1540-580x/2022.2182
Laura Katakowski, S. Hewlings
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Abstract

Objectives: The purpose of this study was to analyze and evaluate evidence supporting curcumin lowering the systemic inflammatory marker, CRP in humans. Methods: A systematic literature search was completed using PubMed and MEDLINE databases. Results: After inclusion and exclusion criteria, 9 studies were evaluated, and the percent change of CRP blood levels was calculated and analyzed. Results: The results for these studies show strong statistical significance for the C3 complex with Bioperine and nano curcumin. Bioactive curcumin exhibits a higher percent decrease of blood level CRP than trials using only curcumin or turmeric. Conclusion: Overall bioactive curcumin/ curcumin with Bioperine are alternative treatments for lowering the systemic inflammation marker, CRP.
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生物活性姜黄素及其降低全身性炎症作用的CRP测定:一项系统综述
目的:本研究的目的是分析和评价支持姜黄素降低人体全身炎症标志物CRP的证据。方法:使用PubMed和MEDLINE数据库进行系统的文献检索。结果:根据纳入和排除标准,评估9项研究,计算并分析CRP血水平变化百分比。结果:C3与生物碱、纳米姜黄素的配合物具有较强的统计学意义。与仅使用姜黄素或姜黄相比,生物活性姜黄素显示出更高百分比的血液CRP水平下降。结论:姜黄素/姜黄素联合生物碱是降低全身炎症标志物CRP的替代治疗方法。
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自引率
25.00%
发文量
18
审稿时长
35 weeks
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