Accuracy of High Resolution Multidetector Computed Tomography in the Local Staging of Rectal Cancer

R. Ramanan, V. Munikrishnan, A. Venkataramanan, S. Swain, Kaveripattu Sathiyamurthy Sunilkumar, Vadanika Venu, M. Hariharan, Mohammad Zehran Saipillai, A. Ahamed
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Abstract

Abstract Background Magnetic resonance imaging (MRI) is the gold standard for local staging of rectal cancer. Advanced computed tomography (CT) machines are now capable of high-resolution images of rectal cancer and utilized for CT perfusion. The possibility of local staging of rectal cancer by CT needs to be explored. Purpose The aim of the study is to evaluate accuracy of high-resolution CT for local rectal cancer staging. Methods A high-resolution CT was performed for local staging of rectal cancer in our study group of 93 patients, where 64 underwent primary surgery and 29 underwent surgery post neoadjuvant chemoradiotherapy (NACRT). Results In differentiating stages T2-and-less than T2 from T3–T4 rectal cancer, accuracy, sensitivity, specificity, and kappa score in overall patients were 91%, 87%, 94%, and 0.8; in primary surgery group were 89%, 76%, 94%, and 0.7; in NACRT group were 97%, 100%, 94%, and 0.9; in low rectal group were 94%, 89%, 97%, and 0.82, respectively. Conclusion High resolution CT is an accurate tool for local staging of rectal cancer.
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高分辨率多探测器计算机断层扫描在直肠癌局部分期中的准确性
磁共振成像(MRI)是直肠癌局部分期的金标准。先进的计算机断层扫描(CT)机器现在能够提供高分辨率的直肠癌图像,并用于CT灌注。CT对直肠癌局部分期的可能性有待探讨。目的评价高分辨率CT对局部直肠癌分期的准确性。方法对93例直肠癌患者进行高分辨率CT局部分期,其中64例行原发性手术,29例行术后新辅助放化疗(NACRT)。结果鉴别T2期及以下T2期与T3-T4期直肠癌,总体患者的准确性、敏感性、特异性和kappa评分分别为91%、87%、94%和0.8;原发性手术组分别为89%、76%、94%、0.7%;NACRT组分别为97%、100%、94%、0.9;低位直肠组分别为94%、89%、97%和0.82。结论高分辨率CT是准确判断直肠癌局部分期的工具。
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