{"title":"Diverse roles of oxytocin","authors":"Sung Hye Kim, P. Bennett, V. Terzidou","doi":"10.14800/ICS.739","DOIUrl":null,"url":null,"abstract":"The oxytocin/oxytocin receptor (OT/OTR) system has been reported to influence a variety of physiological, behavioural, and emotional processes in humans. There are a wide range of studies focusing on their role in parturition, lactation and behaviour. More recent studies have investigated the novel effects of OT/OTR system including inflammation and miRNAs, as well as the effect of their genetic polymorphisms on the onset of labour and parturition. OT also appears to have a great influence in cardiomyocyte differentiation and heart homeostasis, and an age-specific regulation of muscle maintenance and regeneration. This review will summarize the previously established role of OT/OTR system as well as the studies on their novel roles, and highlight the potential therapeutic approaches.","PeriodicalId":13679,"journal":{"name":"Inflammation and cell signaling","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inflammation and cell signaling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14800/ICS.739","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The oxytocin/oxytocin receptor (OT/OTR) system has been reported to influence a variety of physiological, behavioural, and emotional processes in humans. There are a wide range of studies focusing on their role in parturition, lactation and behaviour. More recent studies have investigated the novel effects of OT/OTR system including inflammation and miRNAs, as well as the effect of their genetic polymorphisms on the onset of labour and parturition. OT also appears to have a great influence in cardiomyocyte differentiation and heart homeostasis, and an age-specific regulation of muscle maintenance and regeneration. This review will summarize the previously established role of OT/OTR system as well as the studies on their novel roles, and highlight the potential therapeutic approaches.
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