A Mini Review on Bioequivalence & the Bioavailability Study on Anticancer Drugs

Abstract

Bioavailability has been one of the most important properties for the formulation to be an effective. The poor oral bioavailability and solubility of several anti-cancer drugs has challenged the scientists all over the world to think differently than the traditional drug delivery system. Recently, the use of natural polymer has been increased to increase the bioavailability of these drugs. Casein polymer has shown to be promising in increasing the bioavailability of the anticancer drugs due to its amphiphilic nature which can bind both hydrophilic and hydrophobic drugs. Due to the nature of the casein it has drawn the attention of the scientists all over the world. In this review, we have focused on the work of various scientists in increasing the oral bioavailability of poorly bioavailable anticancer drugs.