{"title":"Biological agent detection and identification by the Block II Chemical Biological Mass Spectrometer","authors":"W. Griest, M. Wise, K. J. Hart, S. A. Lammert, C. V. Thompson, A. Vass","doi":"10.1002/FACT.1019","DOIUrl":null,"url":null,"abstract":"The Block II Chemical Biological Mass Spectrometer (CBMS) detects and identifies both chemical and biological warfare agents. Biodetection is based upon respirable particle collection by an opposed-jet virtual impactor, liberation of derivatized biomarkers by thermolysis-methylation and their analysis by direct-sampling ion trap mass spectrometry in the full-scan chemical ionization mode. Results from laboratory and field trials demonstrate the capability of the Block II CBMS for biodetection and identification. © 2001 John Wiley & Sons, Inc.Field Analyt Chem Technol 5: 177–184, 2001","PeriodicalId":12132,"journal":{"name":"Field Analytical Chemistry and Technology","volume":"10 1","pages":"177-184"},"PeriodicalIF":0.0000,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"28","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Field Analytical Chemistry and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/FACT.1019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 28
使用Block II化学生物质谱仪对生物制剂进行检测和鉴定
Block II化学生物质谱仪(CBMS)检测和识别化学和生物战剂。生物检测的基础是通过反向喷射虚拟撞击器收集可吸入颗粒，通过热裂解甲基化释放衍生生物标志物，并在全扫描化学电离模式下通过直接采样离子阱质谱法进行分析。实验室和现场试验的结果表明，Block II CBMS具有生物检测和鉴定的能力。©2001 John Wiley & Sons, Inc.Field analyst Chem technology 5: 177-184, 2001
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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