My Hair Guides My Bioelement Dietary Requirements

Momcilovic Berislav, Morovic Sandra, Morovic Jadran
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Abstract

: Background. The bio element nutritional status may be defined as deficient, adequate, or excessive/toxic. Non-invasive method of hair collection makes it a tissue of choice for multi bio element analysis in precision medicine and nutritional epidemiology. Methods. Hair multi bio element profile of healthy 1073 subjects (339 Men. 734Women) was analyzed with the ICP MS. The frequency distribution of the hair log concentration data was used to assess the bio element nutritional status with the median derivatives bioassay. The assay allows for the reliable assessment of the bio element deficiency, adequacy, and excess. Results. Nutritional status of P, Zn, and the bio element pairs of I and Se, Ca and Mg, and Na and K are fully exposed and illustrated. The nutritional status of all twenty two hair bio elements are presented in Table 1 in their decreasing order of abundance (µg·g -1 ): Calcium, Zinc, Phosphorus, Sodium, Potassium, Magnesium, Silicon, Copper, Iron, Aluminum, Boron, Strontium, Chromium, Iodine, Selenium, and in (ng·g -1 ) for Nickel, Manganese, Molybdenum, Silver, Lithium, Cobalt and Gold. Conclusion. Hair bio element median derivatives bioassay proved to be a rapid, reliable, accurate, and fully reproducible method for assessing the bio element nutritional status, the nutritional health surveillance, and maintenance in precision medicine.
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我的头发指导我的生物元素饮食需求
:背景。生物元素的营养状况可以定义为缺乏、充足或过量/有毒。无创毛发采集方法使其成为精密医学和营养流行病学中多生物元素分析的首选组织。方法。采用ICP ms分析了1073名健康受试者(男性339人,女性734人)的头发多种生物元素谱。利用头发对数浓度数据的频率分布,采用中位衍生物生物测定法评估生物元素营养状况。该分析允许对生物元素缺乏、充足和过量进行可靠的评估。结果。P、Zn和I、Se、Ca、Mg、Na、K等生物元素对的营养状况得到了充分的揭示和说明。所有22种毛发生物元素的营养状况按丰度递减顺序(µg·g -1)列在表1中:钙、锌、磷、钠、钾、镁、硅、铜、铁、铝、硼、锶、铬、碘、硒,以及镍、锰、钼、银、锂、钴和金的营养状况(ng·g -1)。结论。毛发生物元素中位衍生物生物测定法被证明是一种快速、可靠、准确、可完全重复的方法,可用于精确医学中生物元素营养状况的评估、营养健康监测和维持。
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