Diagnostic Significance of Uric Acid, C Reactive Protein, Magnesium in Acute Myocardial Infarction

C. Mani, Avapati Raja Sekhar, A SuryaKanth, T. Chandra
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Abstract

Introduction: Study was undertaken to note the levels of high sensitive C-reactive protein (hs-CRP), serum uric acid, serum magnesium levels in acute myocardial infarction (MI). Material and methods: This study was conducted in GSL Medical College, study was approved by institutional ethical committee. Participants were recruited by folloing inclusion and exclusion criteria. After getting detailed history of patient’s blood samples were taken for hemoglobin, blood urea, serum creatinine, uric acid, serum electrolytes, hs CRP, serum uric acid, serum Magnesium. All the participants were subjected to ECG and ECHO cardiography. Fischer’s exact Chi square test was to find statistical analysis, P<0.05 was considered as statistically significant. Results: Of the 100 study participants, 39% participants’ hs CRP levels were ≤3mg/dl; statistically the difference was significant. When serum ureic acid considered, 46% patients with uric acid levels were ≤7mg/dl 66% participants’ magnesium levels were > 1.4mg/dl; The difference was statistically significant. Conclusion: The above findings showed a positive correlation of elevated hs CRP and uric acid; and low magnesium with various risk factors of MI.
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尿酸、C反应蛋白、镁在急性心肌梗死中的诊断意义
本研究旨在观察急性心肌梗死(MI)患者的高敏c反应蛋白(hs-CRP)、血清尿酸、血清镁水平。材料和方法:本研究在GSL医学院进行,经机构伦理委员会批准。按照纳入和排除标准招募受试者。在获得患者详细的病史后,采集了血红蛋白、尿素、血清肌酐、尿酸、血清电解质、hs CRP、血清尿酸、血清镁。所有参与者均接受心电图和超声心动图检查。Fischer的精确卡方检验是发现统计分析,P为1.4mg/dl;差异有统计学意义。结论:hs CRP升高与尿酸呈正相关;低镁与心肌梗死的各种危险因素有关。
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