Relationship Between CD4+ Cell with GenExpert Molecular Mycobacterium tuberculosis Test in HIV/AIDS patients

Al’fira Gita Islami, Rizana Fajrunni’mah, Mega Mirawati
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Abstract

CD4+ cells in HIV/AIDS patients is an examination that serves to monitor the regulation of the immune system. HIV/AIDS patients experience a decrease in the number of CD4+ cells which results in various opportunistic infections, one of which is caused by Mycobacterium tuberculosis. This study aims to determine the relationship between the results of CD4+ cell with GenExpert Molecular Mycobacterium tuberculosis Test. This study was based on an analytic observational cross-sectional design on 53 samples of HIV/AIDS patients at Budhi Asih Hospital. Data analyze using Fisher Exact statistical test with α = 0.05. The result showed percentage CD4+ cells <200 with positive TCM result 48 (86,4%). CD4+ cells >200 with GenExpert positif result 0 (0,0%). The results showed that there was no relationship between CD4+ cell examination and TCM GenExpert MTB examination in HIV/AIDS patients (p = 0.574). From the result we can conclude that maybe other infection has happened.
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HIV/AIDS患者CD4+细胞与GenExpert分子结核分枝杆菌检测的关系
HIV/AIDS患者体内CD4+细胞的检测是一种监测免疫系统调节的检测方法。艾滋病毒/艾滋病患者的CD4+细胞数量减少,导致各种机会性感染,其中一种是由结核分枝杆菌引起的。本研究旨在确定CD4+细胞检测结果与GenExpert分子结核分枝杆菌检测结果的关系。本研究基于对Budhi Asih医院53例HIV/AIDS患者样本的分析观察性横断面设计。数据分析采用Fisher精确统计检验,α = 0.05。结果显示CD4+细胞百分比为200,GenExpert阳性结果为0(0,0%)。结果显示,HIV/AIDS患者CD4+细胞检测与TCM GenExpert MTB检测无相关性(p = 0.574)。从结果我们可以得出结论,可能发生了其他感染。
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