Comparitive Invitro Antihelmintic Activity of Electeria cardamom and Amomum subulatum against Pheritima Posthuma

Abstract

Elettaria cardamomum and Amomum subulatum fruits were easily available and commonly used in our day –to-day life. The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous extracts of fruits of Elettaria cardamomum, Amomum subulatum and mixed. The fruits were extracted separately with distilled water by maceration method .The various concentrations of the extract (50,100, 200mg/ml) respectively were screened for their anthelmintic activity using Pheritima posthuma. The activity was comparable with the standard drug albendazole. When the concentrations of the extract are increased, a gradual increase in anthelmintic activity is observed. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. Aqueous extract of Elettaria cardamomum, Amomum subulatum and mixed showed anthelmintic activity but mixed extract was more efficient anthelmintic activity against Indian earthworms. The data were found statistically significant by using one way ANOVA (P< 0.001). Further studies are suggested to isolate the active principles responsible for the activity.