Hypoglycemic and hypolipidemic potential of turmeric and black cumin in rat model

Abstract

Diabetes Mellitus (DM) is a complex ailment that disturb metabolic process of body and prevalent worldwide. Natural products have gained substantial consideration in correcting diabetes and its associated level globally. This research is conducted to access the therapeutic potential of turmeric and black cumin to lessen the diet related malfunctioning like diabetes mellitus which is defined by elevated blood glucose level. Turmeric and black cumin both possess disease prevention properties like anti-diabetic, anti-hyperlipidemic, antioxidants and numerous others. Therapeutic effect of turmeric and black cumin was assessed by an efficacy study on streptozotocin induced diabetic rats. Rats were divided into 5 groups that are G0 consist of healthy rats, G1 consist of diabetic rats without giving any treatment, G2 involves diabetic rats received turmeric powder, G3 involves diabetic rats received black cumin powder and G4 consist of diabetic rats treated with combined mixture of turmeric powder and black powder. The objective of this study was to estimate the anti-diabetic role of turmeric and black cumin in rats. The result indicated that blood glucose level and serum lipid profile was greatly improved by combined mixture of turmeric and black cumin rather than the individual doses of turmeric and black cumin. Thus the result showed that turmeric and black cumin has potential to treat diabetes mellitus and related disorders.