Ocular Nanosuspension a Novel Approach – Review

Abstract

Effective ocular medication administration is still a difficulty for pharmaceutical scientists in the current drug delivery situation, despite various scientific endeavours. In the ocular drug delivery system, several topical medication applications in the form of solutions, suspensions, and ointments are used to treat eye infections. As a result of several anatomical and pathophysiological barriers present in the eye, many conventional dose forms have issues with poor ocular bioavailability due to short ocular residence times. Many recent available medications have weak solubility, which causes key challenges during formulation and exhibits poor bioavailability. The issue is significantly more complicated for medications that fall under BCS Class II. Nanotechnology is utilised to increase the solubility and bioavailability of poorly soluble medications in order to solve these issues. This review provides an insight into an overview of ocular challenges to anterior section delivery and strategies for removing these obstacles using nanocarrier technology. In addition to addressing the issues of poor solubility and bioavailability, nanosuppension also impacts the pharmacokinetics of the drug, enhancing its efficacy and safety.