Generalized tetanus: a case report.

M. Shakhmardanov, V. Nikiforov, A. Skryabina, S. Burova, Y. N. Tomilin, A. S. Abusueva, N. Antipyat
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Abstract

Tetanus is a rare disease caused by Clostridium tetani, causing damage to the central nervous system with the development of muscle hypertension and attacks of generalized seizures caused by the action of the pathogen toxin. Despite the availability of safe and effective vaccines, the urgency of the problem of tetanus incidence is high, since a significant part of the population is not immunized against this disease, and severe manifestations of tetanus can be fatal. A clinical case of traumatic generalized tetanus in an 11-year-old patient is described. The absence of routine immunization against tetanus and emergency active-passive immunization contributed to the development of the disease. The disease proceeded in a typical form with the development of muscle spasm, myoclonia, trism, convulsions. Specific tetanus serum was treated, pathogenetic therapy with anticonvulsants and muscle relaxants was performed against the background of which clinical recovery occurred and the patient was discharged from the hospital.
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广泛性破伤风1例报告。
破伤风是一种罕见的由破伤风梭菌引起的疾病,可引起中枢神经系统的损害,并发肌肉高血压,并在病原体毒素的作用下引起全身性癫痫发作。尽管有安全有效的疫苗,但破伤风发病率问题的紧迫性很高,因为很大一部分人口没有接种这种疾病的疫苗,而且破伤风的严重表现可能是致命的。一个临床病例外伤性广泛性破伤风在一个11岁的病人是描述。常规破伤风免疫和紧急主-被动免疫的缺乏促成了该病的发展。该疾病以典型的形式发展为肌肉痉挛、肌阵挛、震颤、抽搐。在临床康复和患者出院的背景下,给予特异性破伤风血清治疗,并给予抗惊厥药和肌肉松弛药进行病理治疗。
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