JGI Fungal Genomics Program

I. Grigoriev
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引用次数: 1

Abstract

Genomes of energy and environment fungi are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 60 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such `parts? suggested by comparative genomics and functional analysis in these areas are presented here.
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JGI真菌基因组计划
能源和环境真菌的基因组是美国能源部联合基因组研究所真菌基因组计划的重点。其重点项目真菌基因组百科全书,针对与植物健康(共生体,病原体和生物防治剂)和生物精炼过程(纤维素降解,糖发酵,工业宿主)相关的真菌,并通过基因组测序和分析探索真菌多样性。迄今为止,JGI已经对60多个真菌基因组进行了测序,并通过真菌门户网站MycoCosm (www.jgi.doe.gov/fungi)发布,该网站将序列和功能数据与基因组分析工具相结合,面向用户社区。在功能基因组学的支持下,序列分析有助于开发从生物燃料作物生态系统到生物精炼厂等复杂系统的部件清单。最近有这样的例子吗?本文介绍了比较基因组学和功能分析在这些方面的建议。
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