Study of Antibiotics Prescribing Pattern in Paediatric Patients of ThamarProvince, in Republic of Yemen

A. Maa, Al'-Kadi Km, Alawdi Sm
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Abstract

The aim of this study was to determine the prescriptions pattern of antibiotic in paediatric in-patient department of General Thamar Hospital in Yemen. The method was prospective and observational study which was carried out for 2 months duration between March- April 2015. Patient’s data was being recorded in a specific format and results were analysed by descriptive statistic and expressed as mean ± SD. The result was out of 148 patients, 95 prescriptions were taken antibiotics, where 59 were male child and 36 were female child. The mean age of patient on antibiotic was 1.49 ± 2.12 years. The total antibiotics were prescribed to the patients was 194 and the average number of antibiotics per prescription was 2.04 ± 0.55. The most prevalent diseases among studied patients was bronchitis (27.4%) followed by asthma (15.8%), and lower respiratory tract infection (9.5%). Cephalosporin (51.5%) was found to be widely prescribed antibiotic followed by penicillin (25.3), aminoglycosides (13.4), metronidazole (5.7%), vancomycin (2.6%), and azithromycin. The most of the antibiotics were administered for inpatients 183 (94.3%) prescribed parenteral, and 11 (5.7%) prescribed oral. The conclusion of study was Ceftriaxone and penicillin was identified to be the most prescribed medications in the General Thamar hospital. The selection of antibiotic should be based on culture and sensitivity test to avoid the development of bacterial resistance; however prescription of antibiotic should be done in accordance with WHO guidelines and rational strategies.
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也门共和国塔马省儿科患者抗生素处方模式研究
本研究的目的是确定也门塔马尔总医院儿科住院部抗生素的处方模式。方法为前瞻性观察性研究,于2015年3 - 4月进行为期2个月的研究。患者资料以特定格式记录,结果用描述性统计分析,并以mean±SD表示。结果148例患者中,95例患者开了抗生素处方,其中男59例,女36例。患者使用抗生素的平均年龄为1.49±2.12岁。患者共使用抗生素194种,平均处方抗生素数为2.04±0.55种。最常见的疾病是支气管炎(27.4%),其次是哮喘(15.8%)和下呼吸道感染(9.5%)。头孢菌素(51.5%)是被广泛使用的抗生素,其次是青霉素(25.3%)、氨基糖苷类(13.4%)、甲硝唑(5.7%)、万古霉素(2.6%)和阿奇霉素。住院患者使用抗生素最多的是肠外处方183例(94.3%),口服11例(5.7%)。研究的结论是头孢曲松和盘尼西林是塔马尔总医院最常用的处方药。抗生素的选择应以培养和药敏试验为基础,避免细菌产生耐药性;然而,抗生素的处方应按照世卫组织的指导方针和合理的策略进行。
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