The Effect of Hevea Bransiliensis Natural Rubber on Weight Gain and Plasma Cholesterol Concentration of Experimental Rats

B. Abubakar, U. NjokuO., S. Suleiman, Ozougwu V.E.O, A. Chidozie, C. OkonkwoC.
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Abstract

The effects of Hevea bransiliensis natural rubber on weight gain and plasma cholesterol concentration of experimental rats were analyzed. Forty albino wister rats of either sex weighing 140-450g were used. The rats were divided into five equal groups marked A, B, C, D and E of eight rats each, and each group was fed on different dietary regime A, B, C, D and E respectively as indicated in tables 1 and 2. Diet A, (the control) had no rubber seed oil in the diet, whereas diets B, C, D and E (the experimental) had 2% refined rubber seed oil, 2% crude rubber seed oil, 4% refined rubber seed oil and 4% crude rubber seed oil by weight incorporated respectively. The results showed a general increase in mean weight with duration of feeding. Group D (4% refined rubber seed oil incorporated in the diet) showed more rapid increase in mean weights than groups E (4% crude rubber seed oil) and A (the control no rubber seed oil). The results also indicated a general increase in total and free plasma cholesterol levels of the rats within eight weeks duration of the feeding and fall during the remaining four weeks.
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橡胶树天然橡胶对实验大鼠增重及血浆胆固醇浓度的影响
分析了橡胶树天然橡胶对实验大鼠增重和血浆胆固醇浓度的影响。选取体重140-450g的白化大鼠各40只。将大鼠分为5组,每组8只,标记为A、B、C、D、E,每组分别饲喂A、B、C、D、E不同的饲粮方案,如表1、2所示。饲粮A(对照组)不添加橡胶籽油,饲粮B、C、D和E(试验组)分别添加2%的精炼橡胶籽油、2%的粗橡胶籽油、4%的精炼橡胶籽油和4%的粗橡胶籽油。结果显示,随着饲养时间的延长,平均体重普遍增加。D组(饲粮中添加4%精炼橡胶籽油)的平均体重增加速度快于E组(饲粮中添加4%粗橡胶籽油)和A组(对照组不添加橡胶籽油)。结果还表明,大鼠的血浆总胆固醇和游离胆固醇水平在喂食的八周内普遍升高,在其余四周内下降。
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