Antioxidative and Antimicrobial Activities of Rhodiola rosea Root as a Cosmetic Material

B. Lee, Jin-Kwon Ahn
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引用次数: 1

Abstract

Purpose: This study aimed to examine the antioxidant and antibacterial activities of Rhodiola rosea (R. rosea) root hot water extract as a cosmetic material.Methods: R. rosea root was extracted with hot water and used as a sample. Total polyphenol content, total flavonoid content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity of R. rosea root hot water extract were analyzed to measure antioxidant effects. Additionally, the antibacterial effect on Staphylococcus aureus (S. aureus), a skin-like fungus, was measured using the paper disk method.Results: The DPPH radical scavenging activity and ABTS radical scavenging activity of R. rosea root hot water extract was 57.88% and 93.13%, respectively, at 1 mg/ mL. The total polyphenol and flavonoid concentrations were 375.30±4.63 μg/mL and 497.82±19.55 μg/mL, respectively. The paper disk method for the antibacterial effect on S. aureus showed clear zones at a concentration of 0.01–10 mg/mL.Conclusion: The antioxidant and antibacterial effects of R. rosea root hot water extract were confirmed, confirming its potential as a cosmetic material.
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化妆品原料红景天根的抗氧化和抗菌活性研究
目的:研究红景天(R. rosea)根热水提取物作为化妆品原料的抗氧化和抗菌活性。方法:采用热水浸提法提取红迭根作为样品。研究了红叶根热水提取物的总多酚含量、总黄酮含量、2,2-二苯基-1-苦酰肼(DPPH)自由基清除能力和2,2'-氮化萘-3-乙基苯并噻唑啉-6-磺酸(ABTS)自由基清除能力。此外,还采用纸片法测定了其对皮肤样真菌金黄色葡萄球菌(S. aureus)的抑菌效果。结果:在1 mg/ mL浓度下,红芍热水提取物对DPPH自由基和ABTS自由基的清除率分别为57.88%和93.13%,总多酚和类黄酮浓度分别为375.30±4.63 μg/mL和497.82±19.55 μg/mL。纸盘法对金黄色葡萄球菌的抑菌效果在0.01 ~ 10 mg/mL范围内呈现明显的抑菌带。结论:证实了玫瑰根热水提取物的抗氧化和抗菌作用,证实了其作为化妆品原料的潜力。
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