A Pilot Study of Serum Parathyroid Hormone in Acute Coronary Syndrome

Md. Harisul Hoque, S. Zaman, Khurshid Ahmed, Md Faisal Ibne Kabir, N. Fatema
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Abstract

Acute coronary syndrome (ACS) is the public health issue as it is the single most common cause of death in the world. Role of vitamin D in cardiovascular health is of much interest at present. Experimental, as well as, some observational studies suggest that vitamin D and its metabolites are integrally related to blood pressure and the rennin-angiotensin system. Vitamin D insufficiency affects almost 50% of the population worldwide. Few studies have been carried out to determine the prevalence of hypovitaminosis D in Bangladesh . 30 Patient with ACS were included in this study who had admitted in the department of Cardiology of Bangabandhu Sheikh Mujib Medical University (BSMMU) patient with in first 48 hours of the onset of chest pain. This study was conducted from 1st  July’18 to 30th  June’19 (One year) by Purposive sampling. Data analysis was carried out by using the statistical package for Social Science (SPSS) version 20.0 windows software. Baseline characteristics have been compared using the independent sample student t-test test where appropriate. The student t-test was used to assess the correlation between PTH levels. p-value <0.05 was taken as significant. We found an association between elevated PTH levels and ACS. University Heart Journal Vol. 16, No. 2, Jul 2020; 71-77
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急性冠状动脉综合征血清甲状旁腺激素的初步研究
急性冠脉综合征(ACS)是一个公共卫生问题,因为它是世界上最常见的死亡原因。维生素D在心血管健康中的作用是目前人们非常感兴趣的。实验和一些观察性研究表明,维生素D及其代谢物与血压和肾素-血管紧张素系统完全相关。维生素D不足影响着全球近50%的人口。很少有研究确定孟加拉国维生素D缺乏症的患病率。本研究纳入Bangabandhu Sheikh Mujib医科大学(BSMMU)心内科收治的30例ACS患者,患者在48小时内出现胸痛。本研究于2018年7月1日至2019年6月30日(一年)采用有目的抽样方法进行。采用SPSS 20.0版windows软件进行数据分析。基线特征在适当的情况下使用独立样本学生t检验进行比较。采用学生t检验评估甲状旁腺激素水平之间的相关性。p值<0.05为显著性。我们发现甲状旁腺激素水平升高与ACS之间存在关联。《大学心脏杂志》第16卷第2期,2020年7月;71 - 77
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