Cu2+ Complexes with the Simplest Amino Acid Glycine (Gly)

Yahia Z. Hamada, Nyasha J. Makoni, H. Hamada
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引用次数: 6

Abstract

Most Biology/Chemistry/Physicists and Medicinally related researchers think that the commonly known 20 Amino acids (AA) have been studied to the extent that they know almost everything about them. We believe that studying the simplest amino acid Glycine (Gly) is not that simple when it comes to its reactions with metal ions especially in aqueous solutions under ambient conditions. It is known that Gly is an inhibitory neurotransmitter [1-3]. Typically a 70 kg human body contains about 280 mg copper (Cu2+). The copper ion concentration in seawater is in the range of one micro-molar or (1.0x10-3 mM), while the human Extracellular Blood Plasma concentration of Cu2+ is ~1.5 x10-2 mM [1].
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Cu2+与最简单氨基酸甘氨酸(Gly)配合物
大多数生物学/化学/物理学家和医学相关的研究人员认为,众所周知的20种氨基酸(AA)已经被研究到几乎了解它们的一切的程度。我们认为,研究最简单的氨基酸甘氨酸(Gly)与金属离子的反应并不那么简单,特别是在环境条件下的水溶液中。已知Gly是一种抑制性神经递质[1-3]。一般来说,一个70公斤的人体含有约280毫克铜(Cu2+)。海水中的铜离子浓度在1微摩尔或(1.0 × 10- 3mm)范围内,而人的细胞外血浆Cu2+浓度为~1.5 × 10- 2mm[1]。
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