Liposomal Drug Delivery System-A Review

Abstract

Purpose of this paper: Liposomes have received a lot of attention during the past 30 years as pharmaceutical carriers of great potential. More recently, many developments have been seen in the area of liposomal drugs-from clinically approved products to new experimental applications. For further successful development of this field, promising trends must be identified and exploited, with a clear understanding of the limitations of these approaches. Design/methodology/approach: This review presents a panoramic view of current status of research in this field to serve as a ready reference for future researchers. Practical implications: The treasure of information provided in this review find wide utility by future researchers and will serve as basis for further improvement in methodology and design of better formulations as well as evaluation methods. What is original/value of paper: In this article, basic characteristics, method of preparation and marketed formulations of liposomes are discussed. The success of liposomes as drug carriers has been reflected in a number of liposome based formulations, which are commercially available, or are currently undergoing clinical trials.