Jacek Staszewski , Kazimierz Tomczykiewicz , Bogdan Brodacki , Renata Anna Piusińska-Macoch , Adam Stępień , Z. Podgajny , P. Smużyński , Maciej Zarębiński
{"title":"An increased frequency of right-to-left shunt in patients with chronic hyperventilation syndrome","authors":"Jacek Staszewski , Kazimierz Tomczykiewicz , Bogdan Brodacki , Renata Anna Piusińska-Macoch , Adam Stępień , Z. Podgajny , P. Smużyński , Maciej Zarębiński","doi":"10.1016/j.permed.2012.02.027","DOIUrl":null,"url":null,"abstract":"<div><p>Relation of right-to-left shunt (RLS) with chronic hyperventilation syndrome (CHVS) has not been previously reported. We evaluated the prevalence of RLS in patients with CHVS. Patients with CHVS and 25 healthy controls (CG) were recruited into the study. Vascular RLS was diagnosed using contrast TCD. Of 25 subjects with CHVS, 16 (64%) had RLS vs 3 from CG (12%). TEE confirmed PFO in 10 patients with CHVS (40%) vs 2 from CG (8%). Pulmonary AVM was found in chest CT in 2 patients (10%) with CHVS and none from CG. The prevalence of RLS and PFO in patients with CHVS was significantly higher than in healthy subjects.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 241-243"},"PeriodicalIF":0.0000,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.027","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Perspectives in Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211968X12000344","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Relation of right-to-left shunt (RLS) with chronic hyperventilation syndrome (CHVS) has not been previously reported. We evaluated the prevalence of RLS in patients with CHVS. Patients with CHVS and 25 healthy controls (CG) were recruited into the study. Vascular RLS was diagnosed using contrast TCD. Of 25 subjects with CHVS, 16 (64%) had RLS vs 3 from CG (12%). TEE confirmed PFO in 10 patients with CHVS (40%) vs 2 from CG (8%). Pulmonary AVM was found in chest CT in 2 patients (10%) with CHVS and none from CG. The prevalence of RLS and PFO in patients with CHVS was significantly higher than in healthy subjects.
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