Bromelain-based enzymatic debridement in hand burns – an easier way to manage a difficult patient: case report

T. Neagu, Eliza Bordeanu-Diaconescu, M. Tiglis, I. Peride, I. Lascar
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Abstract

Introduction. Bromelain-based enzymatic debridement may be considered the standard in patients with upper extremity burns management, regarding the low risk of bleeding, wound infections, reduction of surgical timing, and the decreased risk of compartment syndrome development. Case presentation. We present the case of hand and face burns in a patient presenting deep venous thrombosis of the lower limb extended to the level of the vena cava, and bilateral pulmonary embolism. The enzymatic debridement reduced periprocedural bleeding and allowed a faster recovery and therefore the resumption of oral anticoagulation and antiplatelet medication in a patient with important cardiac, arterial, and renal comorbidities. Conclusion. Bromelain-based enzymatic debridement use is recommended in patients presenting upper limb deep burns, especially in anatomically challenging areas, like hand fingers, and especially in those with a previous medical history that predisposes them to periprocedural bleeding and increased risk of poor healing.
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以菠萝蛋白酶为基础的手烧伤酶清创——一种处理难治性病人的简便方法:病例报告
介绍。基于菠萝蛋白酶的酶清创可以被认为是上肢烧伤患者治疗的标准方法,因为出血、伤口感染的风险低,减少了手术时间,降低了筋膜室综合征发生的风险。案例演示。我们提出的情况下,手和脸烧伤的病人呈现下肢深静脉血栓形成延伸到腔静脉的水平,和双侧肺栓塞。酶清创减少术中出血,使恢复更快,因此对有重要心脏、动脉和肾脏合并症的患者恢复口服抗凝和抗血小板药物治疗。结论。建议对上肢深度烧伤的患者使用菠萝蛋白酶酶清创,特别是在解剖上具有挑战性的部位,如手指,特别是那些既往病史易导致术中出血和愈合不良风险增加的患者。
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