T. Aninditha, Ansi Rinjani, Gurmeet Singh, Rahmad Mulyadi, Rini Andriani, N. A. Mulansari
Background and objectives. The incidence of brain metastases is higher than primary brain tumors, with lung cancer as a common etiology at “Dr. Cipto Mangunkusumo” General Hospital. Delay in diagnosis can cause brain herniation, resulting in disability and death. We aimed to investigate the compatibility between daily clinical practice and clinical practice guidelines for diagnosing brain metastases due to lung cancer at “Dr. Cipto Mangunkusumo” General Hospital while also examining factors that might influence the duration of the diagnosis. Materials and methods. We conducted a retrospective cohort study to determine the conformity between the duration of diagnosis of metastatic brain tumors due to lung cancer in daily clinical practice with clinical practice guidelines. Secondary data was obtained from medical records from November 2021 until June 2022. Results. Twelve subjects (30%) were diagnosed with brain metastases from lung cancer within two weeks with a median duration of 18.5 days (IQR 12-34 days). The duration of 7 days (IQR 4-11 days) was required to obtain a lung mass, 8 days (IQR 4.5-13 days) to perform a biopsy, and 6 days (IQR 3.5-7 days) to obtain t pathology results. No statistically significant relationship exists between the variables assessed and the duration of diagnosis. Conclusions. The clinical practice guidelines at “Dr. Cipto Mangunkusumo” General Hospital for diagnosing brain metastases from lung cancer within two weeks could only be carried out in 30% of subjects in this study. Collaboration between departments is needed to make the diagnosis faster.
{"title":"Diagnosis of brain metastasis due to lung cancer and affecting factors at “Dr. Cipto Mangunkusumo” General Hospital","authors":"T. Aninditha, Ansi Rinjani, Gurmeet Singh, Rahmad Mulyadi, Rini Andriani, N. A. Mulansari","doi":"10.37897/rmj.2024.2.1","DOIUrl":"https://doi.org/10.37897/rmj.2024.2.1","url":null,"abstract":"Background and objectives. The incidence of brain metastases is higher than primary brain tumors, with lung cancer as a common etiology at “Dr. Cipto Mangunkusumo” General Hospital. Delay in diagnosis can cause brain herniation, resulting in disability and death. We aimed to investigate the compatibility between daily clinical practice and clinical practice guidelines for diagnosing brain metastases due to lung cancer at “Dr. Cipto Mangunkusumo” General Hospital while also examining factors that might influence the duration of the diagnosis. Materials and methods. We conducted a retrospective cohort study to determine the conformity between the duration of diagnosis of metastatic brain tumors due to lung cancer in daily clinical practice with clinical practice guidelines. Secondary data was obtained from medical records from November 2021 until June 2022. Results. Twelve subjects (30%) were diagnosed with brain metastases from lung cancer within two weeks with a median duration of 18.5 days (IQR 12-34 days). The duration of 7 days (IQR 4-11 days) was required to obtain a lung mass, 8 days (IQR 4.5-13 days) to perform a biopsy, and 6 days (IQR 3.5-7 days) to obtain t pathology results. No statistically significant relationship exists between the variables assessed and the duration of diagnosis. Conclusions. The clinical practice guidelines at “Dr. Cipto Mangunkusumo” General Hospital for diagnosing brain metastases from lung cancer within two weeks could only be carried out in 30% of subjects in this study. Collaboration between departments is needed to make the diagnosis faster.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"52 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141381754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fidelia Elvira Da Costa Rao, Femi Syahriani, H. Rasyid, S. Bakri, Harun Iskandar, M. N. Mustari, Gerald Wonggokusuma, A. A. Zainuddin, Fidelia Elvira Da, ID CostaRaoORCID
Background and aim. One of the most prevalent chronic joint illnesses is osteoarthritis (OA), which can impair a patient's quality of life by causing joint pain, stiffness, deformity, and narrowed joint spaces. Many factors influence the pathogenesis of Osteoarthritis such as age and body weight, as well as genetic factors that are reported to play a role in the occurrence and progression of Osteoarthritis. Recently, many studies have demonstrated that inflammatory variables contribute to osteoarthritis pathomechanisms. It is currently thought that inflammatory variables alone are an independent risk factor for osteoarthritis. Methods. Observational sub-analysis with a cross-sectional approach to examine the relationship between Angiotensin Converting Enzyme 1 (ACE 1) levels and the grading of osteoarthritis at “Dr. Wahidin Sudirohusodo” Hospital from October 2020 to February 2021. ACE 1 levels were measured using the Elisa KIT and grading of osteoarthritis using the Kellgren and Lawrence criteria. Results. Analysis of the relationship between ACE 1 levels and osteoarthritis grading using the ANOVA test and Post Hoc Bonferonni Test showed a significant relationship between ACE 1 levels and osteoarthritis grading, where high ACE 1 levels were related to osteoarthritis grading. Deficiency and insufficiency (p<0.05). The results of this study are in line with previous research. Conclusion. The higher the ACE 1 level, the more severe the degree of knee osteoarthritis.
{"title":"Comparison of angiotensin converting enzyme 1 levels to the grading of knee osteoarthritis","authors":"Fidelia Elvira Da Costa Rao, Femi Syahriani, H. Rasyid, S. Bakri, Harun Iskandar, M. N. Mustari, Gerald Wonggokusuma, A. A. Zainuddin, Fidelia Elvira Da, ID CostaRaoORCID","doi":"10.37897/rmj.2024.2.2","DOIUrl":"https://doi.org/10.37897/rmj.2024.2.2","url":null,"abstract":"Background and aim. One of the most prevalent chronic joint illnesses is osteoarthritis (OA), which can impair a patient's quality of life by causing joint pain, stiffness, deformity, and narrowed joint spaces. Many factors influence the pathogenesis of Osteoarthritis such as age and body weight, as well as genetic factors that are reported to play a role in the occurrence and progression of Osteoarthritis. Recently, many studies have demonstrated that inflammatory variables contribute to osteoarthritis pathomechanisms. It is currently thought that inflammatory variables alone are an independent risk factor for osteoarthritis. Methods. Observational sub-analysis with a cross-sectional approach to examine the relationship between Angiotensin Converting Enzyme 1 (ACE 1) levels and the grading of osteoarthritis at “Dr. Wahidin Sudirohusodo” Hospital from October 2020 to February 2021. ACE 1 levels were measured using the Elisa KIT and grading of osteoarthritis using the Kellgren and Lawrence criteria. Results. Analysis of the relationship between ACE 1 levels and osteoarthritis grading using the ANOVA test and Post Hoc Bonferonni Test showed a significant relationship between ACE 1 levels and osteoarthritis grading, where high ACE 1 levels were related to osteoarthritis grading. Deficiency and insufficiency (p<0.05). The results of this study are in line with previous research. Conclusion. The higher the ACE 1 level, the more severe the degree of knee osteoarthritis.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"52 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thanh Xuan Nguyen, Duc Anh Le, Hoai Anh Vu, Thanh Hai Phan, Nhu Hien Pham, Minh Duc Pham
Background. Emergency groin hernia is an understudied research field despite its severity requiring emergency surgery associated with high postoperative morbidity and mortality rates. Therefore, the purpose of this study was to investigate the efficacy, critical technical elements, and management of problems associated with the transabdominal preperitoneal (TAPP) laparoscopic technique for adult patients in need of an emergency groin hernia repair. Methods. We analyzed adult patients who were treated between January 2021 and March 2023 for emergency groin hernia repair. These patients' preoperative data were examined. Results. The surgery was successfully performed on all 21 patients. The duration of the surgery was 71.6 ± 19.7 minutes (range, 45–120 minutes). The hospitalization time was 3.2 ± 2.2 days (range, 2–5 days). Conclusions. The TAPP approach is a secure and efficient method for performing emergency groin hernia repair in adults due to its ability to evaluate hernia content and reduce the incidence of incisional infection.
{"title":"Transabdominal preperitoneal laparoscopic method for treatment of emergency groin hernias in adult patients","authors":"Thanh Xuan Nguyen, Duc Anh Le, Hoai Anh Vu, Thanh Hai Phan, Nhu Hien Pham, Minh Duc Pham","doi":"10.37897/rmj.2024.2.3","DOIUrl":"https://doi.org/10.37897/rmj.2024.2.3","url":null,"abstract":"Background. Emergency groin hernia is an understudied research field despite its severity requiring emergency surgery associated with high postoperative morbidity and mortality rates. Therefore, the purpose of this study was to investigate the efficacy, critical technical elements, and management of problems associated with the transabdominal preperitoneal (TAPP) laparoscopic technique for adult patients in need of an emergency groin hernia repair. Methods. We analyzed adult patients who were treated between January 2021 and March 2023 for emergency groin hernia repair. These patients' preoperative data were examined. Results. The surgery was successfully performed on all 21 patients. The duration of the surgery was 71.6 ± 19.7 minutes (range, 45–120 minutes). The hospitalization time was 3.2 ± 2.2 days (range, 2–5 days). Conclusions. The TAPP approach is a secure and efficient method for performing emergency groin hernia repair in adults due to its ability to evaluate hernia content and reduce the incidence of incisional infection.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atrioventricular conduction disorders represent an alteration in the normal function of the heart’s electrical conduction system, a system that connects the atria and ventricles through the atrio-ventricular node and the His-Purkinje system. Consequently, bradycardia can develop and lead to the occurrence of symptoms (dizziness, loss of consciousness, tachyarrhythmias, heart failure phenomena). Identifying patients at risk of developing atrioventricular conduction disorders will allow early interventions on risk factors and improvements in prognosis. This narrative review explores the risk factors that determine the development and progression of atrioventricular conduction disorders. We will discuss traditional risk factors (age, sex, arterial hypertension, ischemic cardiac disease, diabetes, chronic kidney disease), but also risk factors that are currently being researched (genetic predisposition and inflammatory markers). Finally, we will discuss the limitations and challenges of predicting risk factors for atrioventricular conduction disorders.
{"title":"Predictive factors of atrioventricular conduction disorders","authors":"Carmen Marina Deutsch, E. Bădilă, Adriana Iliesiu","doi":"10.37897/rmj.2024.2.4","DOIUrl":"https://doi.org/10.37897/rmj.2024.2.4","url":null,"abstract":"Atrioventricular conduction disorders represent an alteration in the normal function of the heart’s electrical conduction system, a system that connects the atria and ventricles through the atrio-ventricular node and the His-Purkinje system. Consequently, bradycardia can develop and lead to the occurrence of symptoms (dizziness, loss of consciousness, tachyarrhythmias, heart failure phenomena). Identifying patients at risk of developing atrioventricular conduction disorders will allow early interventions on risk factors and improvements in prognosis. This narrative review explores the risk factors that determine the development and progression of atrioventricular conduction disorders. We will discuss traditional risk factors (age, sex, arterial hypertension, ischemic cardiac disease, diabetes, chronic kidney disease), but also risk factors that are currently being researched (genetic predisposition and inflammatory markers). Finally, we will discuss the limitations and challenges of predicting risk factors for atrioventricular conduction disorders.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"343 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Cahyanur, Tammy Nurhardini, Maria Angela Putri Maharan, Sri Suryo Adiyanti, W. Rajabto, Muhammad Ikhsan, Endang Farihatul Izza
Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.
{"title":"Chronic neutrophilic leukemia: A case report","authors":"R. Cahyanur, Tammy Nurhardini, Maria Angela Putri Maharan, Sri Suryo Adiyanti, W. Rajabto, Muhammad Ikhsan, Endang Farihatul Izza","doi":"10.37897/rmj.2023.3.6","DOIUrl":"https://doi.org/10.37897/rmj.2023.3.6","url":null,"abstract":"Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The article demonstrates that the Romanian scientist Stefan Odobleja (1902-1978), in his work "Consonantist Psychology" elaborated the principles and laws that are the basis of artificial thinking. The fascination with artificial intelligence began last century, when humanity was very far from the technologies without which we cannot imagine life today. Artificial intelligence refers to the phenomenon where a machine acts like a human mind. The history of artificial intelligence can include the scientist Stefan Odobleja, as the father of artificial thinking, described in his work, which is actually a generalized cybernetics.
{"title":"Stefan Odobleja, cybernetics and artificial thinking/Artificial Intelligence","authors":"Nicolae Popescu, Sorin Riga, G. Popescu","doi":"10.37897/rmj.2023.3.8","DOIUrl":"https://doi.org/10.37897/rmj.2023.3.8","url":null,"abstract":"The article demonstrates that the Romanian scientist Stefan Odobleja (1902-1978), in his work \"Consonantist Psychology\" elaborated the principles and laws that are the basis of artificial thinking. The fascination with artificial intelligence began last century, when humanity was very far from the technologies without which we cannot imagine life today. Artificial intelligence refers to the phenomenon where a machine acts like a human mind. The history of artificial intelligence can include the scientist Stefan Odobleja, as the father of artificial thinking, described in his work, which is actually a generalized cybernetics.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"197 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. D. Dănciulescu Miulescu, Diana Loreta Paun, I. Gherlan, Radu Ilinca
Introduction. Type 2 diabetes mellitus (T2DM) is currently an important global health disease. At the same time vitamin D deficiency is considered the other public health problem around the world. Some studies suggest involving insufficient or deficiency of vitamin Din the etiopathogenesis of T2DM. Materials and methods. 58 patients, 33 women (56.89%) and 25 men (43.10%) were included in the observational study. Demographics (age, gender), personal anamnestic data (duration of diabetes, micro-and macrovascular complications, therapy with vitamin D supplements), anthropometric and biochemical parameters were assessed. The anthropometric measurement included height (meters), weight (kg) and body mass index (BMI) defined as a ratio of weight to the square of height (kg/m2). Biochemical parameters included the fasting blood glucose, glycated hemoglobin (HbA1c), serum total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low density lipoprotein (VLDL) cholesterol, triglycerides (TG), as well the level 25(OH)D. We followed the correlation between vitamin D levels and the duration of diabetes, BMI, blood glucose levels, HbA1c, TC, LDL-cholesterol, HDL-cholesterol, VLDL-cholesterol, TG. Results. The average values recorded were 11.72 years for the duration of T2DM, 31.77 kg/m2 for BMI, 169.00 mg/dL for blood glucose levels, 8.01% for HbA1c, 200.40 mg/dL for TC, 129.04 mg/dL for LDL-cholesterol, 47.67 mg/dL for HDL-cholesterol, 26.69 mg/dL for VLDL-cholesterol and 160.34 mg/dL for TG. Conclusion. Following statistical analysis, the observational study highlight statistically negative correlation recorded between the level of vitamin D and BMI, glycemic balance (highlighted by the level of fasting blood glucose and HbA1c). The results found nonsignificant correlation between the levels of vitamin D: duration of diabetes and lipid profile.
导言2 型糖尿病（T2DM）是目前全球重要的健康疾病。与此同时，维生素 D 缺乏也被认为是全球另一个公共卫生问题。一些研究表明，维生素 Din 不足或缺乏与 T2DM 的发病机制有关。材料和方法观察性研究共纳入 58 名患者，其中女性 33 名（56.89%），男性 25 名（43.10%）。研究人员对患者的人口统计学特征（年龄、性别）、个人健康数据（糖尿病病程、微血管和大血管并发症、维生素 D 补充剂治疗情况）、人体测量和生化指标进行了评估。人体测量包括身高（米）、体重（千克）和体重指数（BMI），BMI 的定义是体重与身高的平方之比（千克/平方米）。生化指标包括空腹血糖、糖化血红蛋白（HbA1c）、血清总胆固醇（TC）、高密度脂蛋白（HDL）胆固醇、低密度脂蛋白（LDL）胆固醇、极低密度脂蛋白（VLDL）胆固醇、甘油三酯（TG）以及 25（OH）D 水平。我们跟踪了维生素 D 水平与糖尿病病程、体重指数、血糖水平、HbA1c、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、极低密度脂蛋白胆固醇、甘油三酯（TG）之间的相关性。结果显示所记录的平均值分别为：T2DM 病程 11.72 年；BMI 31.77 kg/m2；血糖水平 169.00 mg/dL；HbA1c 8.01%；TC 200.40 mg/dL；LDL-胆固醇 129.04 mg/dL；HDL-胆固醇 47.67 mg/dL；VLDL-胆固醇 26.69 mg/dL；TG 160.34 mg/dL。结论经过统计分析，该观察性研究突出显示了维生素 D 水平与体重指数、血糖平衡（通过空腹血糖和 HbA1c 水平突出显示）之间的负相关。结果发现，维生素 D 水平与糖尿病病程和血脂状况之间的相关性并不显著。
{"title":"Observational study between level of vitamin D, anthropometric status and metabolic profiles in patients with type 2 diabetes mellitus","authors":"R. D. Dănciulescu Miulescu, Diana Loreta Paun, I. Gherlan, Radu Ilinca","doi":"10.37897/rmj.2023.3.5","DOIUrl":"https://doi.org/10.37897/rmj.2023.3.5","url":null,"abstract":"Introduction. Type 2 diabetes mellitus (T2DM) is currently an important global health disease. At the same time vitamin D deficiency is considered the other public health problem around the world. Some studies suggest involving insufficient or deficiency of vitamin Din the etiopathogenesis of T2DM. Materials and methods. 58 patients, 33 women (56.89%) and 25 men (43.10%) were included in the observational study. Demographics (age, gender), personal anamnestic data (duration of diabetes, micro-and macrovascular complications, therapy with vitamin D supplements), anthropometric and biochemical parameters were assessed. The anthropometric measurement included height (meters), weight (kg) and body mass index (BMI) defined as a ratio of weight to the square of height (kg/m2). Biochemical parameters included the fasting blood glucose, glycated hemoglobin (HbA1c), serum total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low density lipoprotein (VLDL) cholesterol, triglycerides (TG), as well the level 25(OH)D. We followed the correlation between vitamin D levels and the duration of diabetes, BMI, blood glucose levels, HbA1c, TC, LDL-cholesterol, HDL-cholesterol, VLDL-cholesterol, TG. Results. The average values recorded were 11.72 years for the duration of T2DM, 31.77 kg/m2 for BMI, 169.00 mg/dL for blood glucose levels, 8.01% for HbA1c, 200.40 mg/dL for TC, 129.04 mg/dL for LDL-cholesterol, 47.67 mg/dL for HDL-cholesterol, 26.69 mg/dL for VLDL-cholesterol and 160.34 mg/dL for TG. Conclusion. Following statistical analysis, the observational study highlight statistically negative correlation recorded between the level of vitamin D and BMI, glycemic balance (highlighted by the level of fasting blood glucose and HbA1c). The results found nonsignificant correlation between the levels of vitamin D: duration of diabetes and lipid profile.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sura Habeeb Hattab Al-Ani, Ahmad Habeeb Dala Ali, Noordin Othman
Pregnancy is an important event in women’s life as it involves various physiological and anatomical alterations to match and accommodate with the development of the fetus. Due to c-morbidities and pregnancy related complications, pregnant women often requires medical management which includes medication use. We reviewed the literature for studies that assessed medication use among pregnant women in the Arabian countries. Prevalence of medication use among pregnant women from Arabian countries varied from 40% to 98.2%. The most commonly used medications were vitamin and supplements, analgesics, antibiotics, and herbal medicines. The most frequently reported justification for self-medication were: inconvenience, less expensive, previous experience with disease, and that the diseases are not serious. In conclusion, the use of medications during pregnancy were found to be prevalent among pregnant women in the Arabian countries.
{"title":"Medication use during pregnancy in Arab countries: A narrative review","authors":"Sura Habeeb Hattab Al-Ani, Ahmad Habeeb Dala Ali, Noordin Othman","doi":"10.37897/rmj.2023.3.7","DOIUrl":"https://doi.org/10.37897/rmj.2023.3.7","url":null,"abstract":"Pregnancy is an important event in women’s life as it involves various physiological and anatomical alterations to match and accommodate with the development of the fetus. Due to c-morbidities and pregnancy related complications, pregnant women often requires medical management which includes medication use. We reviewed the literature for studies that assessed medication use among pregnant women in the Arabian countries. Prevalence of medication use among pregnant women from Arabian countries varied from 40% to 98.2%. The most commonly used medications were vitamin and supplements, analgesics, antibiotics, and herbal medicines. The most frequently reported justification for self-medication were: inconvenience, less expensive, previous experience with disease, and that the diseases are not serious. In conclusion, the use of medications during pregnancy were found to be prevalent among pregnant women in the Arabian countries.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139331989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria-Andreea Racean, L. Suciu, R. Prișcă, C. Mărginean
Duplication cysts are congenital anomalies that typically have some connection to the gastrointestinal (GI) tract, but in rare cases the cysts can be completed isolated from the GI tract. We present the case of an appropriate for gestational age male infant born at 40 weeks gestational age with neonatal intestinal duplication cyst isolated from the GI tract. Postnatal diagnostic methods included ultrasound (US) and magnetic resonance imaging (MRI) based on abnormal antenatal findings. The positive diagnosis was based on the imaging results. Duplication cysts may remain asymptomatic and that is the reason why antenatal and postnatal US screening plays an important key role in the diagnosis. Series of imaging may confirm the diagnosis, prevent future complication and help the clinician to determine the optimal operative moment.
{"title":"Diagnosis of a rare case of neonatal intestinal duplication cyst isolated from the gastrointestinal tract - Case report","authors":"Maria-Andreea Racean, L. Suciu, R. Prișcă, C. Mărginean","doi":"10.37897/rmj.2023.2.4","DOIUrl":"https://doi.org/10.37897/rmj.2023.2.4","url":null,"abstract":"Duplication cysts are congenital anomalies that typically have some connection to the gastrointestinal (GI) tract, but in rare cases the cysts can be completed isolated from the GI tract. We present the case of an appropriate for gestational age male infant born at 40 weeks gestational age with neonatal intestinal duplication cyst isolated from the GI tract. Postnatal diagnostic methods included ultrasound (US) and magnetic resonance imaging (MRI) based on abnormal antenatal findings. The positive diagnosis was based on the imaging results. Duplication cysts may remain asymptomatic and that is the reason why antenatal and postnatal US screening plays an important key role in the diagnosis. Series of imaging may confirm the diagnosis, prevent future complication and help the clinician to determine the optimal operative moment.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86066985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background. Cancer is a significant health problem worldwide. Globally, cancer is one of the most common causes of morbidity and mortality and this is predicted to increase by at least 70% by 2030. The aim of this systematic review was to identify the state of the scientific evidence regarding the quality of life in patients. with cancer. Methods. The literature was searched in the Scopus, Web of Science and Pub Med databases, the literature related to the quality of life in cancer patients. Keywords are combined with Boolean operators (AND/OR). There are sixty studies were included in the current review. Results. The social and physical domains were the most endangered, while the environment was the most preserved. Comparison between scores showed a significant difference only in terms of self-rated health. The highest scores were found in the group with the best assessment of their health. The results suggest that self-rated health can be a reliable predictor of quality of life in these patients, being important for further studies on this topic. Discussion. The findings of this review indicate low QoL among cancer patients on anticancer therapy. Functional well-being was most affected among cancer patients, followed by emotional well-being among cancer patients on cancer therapy. From our study, it was found that the overall quality of life of the patients was influenced by the education and professional status of the patient. Unemployed and illiterate patients have worse QoL than employed and educated patients.
背景。癌症是一个全球性的重大健康问题。在全球范围内，癌症是最常见的发病和死亡原因之一，预计到2030年这一数字将至少增加70%。本系统综述的目的是确定有关患者生活质量的科学证据的状态。与癌症。方法。这些文献是在Scopus, Web of Science和Pub Med数据库中检索的，这些文献与癌症患者的生活质量有关。关键字与布尔运算符(AND/OR)组合。目前的综述包括了60项研究。结果。社会和自然领域是最濒危的，而环境是最受保护的。分数之间的比较显示，只有在自评健康方面存在显著差异。得分最高的是对自己健康状况评估最好的那一组。结果表明，自评健康可以是这些患者生活质量的可靠预测指标，这对该主题的进一步研究具有重要意义。讨论。本综述的研究结果表明，接受抗癌治疗的癌症患者生活质量较低。癌症患者的功能幸福感受影响最大，其次是接受癌症治疗的癌症患者的情绪幸福感。从我们的研究中发现，患者的整体生活质量受到患者的教育程度和职业状况的影响。失业和文盲患者的生活质量比就业和受过教育的患者差。
{"title":"Quality of life in cancer patients – A systematic review","authors":"Vlora Ejupi, Nexhmije Gori, Astrit M. Gashi","doi":"10.37897/rmj.2023.2.1","DOIUrl":"https://doi.org/10.37897/rmj.2023.2.1","url":null,"abstract":"Background. Cancer is a significant health problem worldwide. Globally, cancer is one of the most common causes of morbidity and mortality and this is predicted to increase by at least 70% by 2030. The aim of this systematic review was to identify the state of the scientific evidence regarding the quality of life in patients. with cancer. Methods. The literature was searched in the Scopus, Web of Science and Pub Med databases, the literature related to the quality of life in cancer patients. Keywords are combined with Boolean operators (AND/OR). There are sixty studies were included in the current review. Results. The social and physical domains were the most endangered, while the environment was the most preserved. Comparison between scores showed a significant difference only in terms of self-rated health. The highest scores were found in the group with the best assessment of their health. The results suggest that self-rated health can be a reliable predictor of quality of life in these patients, being important for further studies on this topic. Discussion. The findings of this review indicate low QoL among cancer patients on anticancer therapy. Functional well-being was most affected among cancer patients, followed by emotional well-being among cancer patients on cancer therapy. From our study, it was found that the overall quality of life of the patients was influenced by the education and professional status of the patient. Unemployed and illiterate patients have worse QoL than employed and educated patients.","PeriodicalId":21278,"journal":{"name":"Romanian Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83601114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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