The identification of the high risk of metabolic syndrome by applying MDR and Jalview bioinformatics programs

Abstract

The metabolic syndrome (MS) is a complex multi-factorial disease associated with obesity (OB), type 1 diabetes (DM1), type 2 diabetes (DM2) and high blood pressure (HBP). The metabolic and nutritional factors, complemented by the interactions between the genome and the environmental conditions mediated by epigenetic mechanisms, and play important role in the genesis of obesity, diabetes mellitus and high blood pressure.1 The purpose of study was to identify the risk of developing MS in patients diagnosed with obesity (OB), DM1, DM2 and high blood pressure (HBP) by using the MDR and Jalview programs, on the basis of clinical, laboratory (biochemical, hematological) and genetic data.