Assessment of relation between periodontal disease and macular degeneration- A clinical study

Harnoor Singh, Avineet Kaur, S. Kansil, Harmandeep Singh Sohi, Jaidev Singh, S. Chatterjee
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Abstract

Background: Periodontal diseases are leading cause of tooth loss. The assessment of correlation between periodontal disease and macular degeneration was performed. Materials and Methods: We enrolled 178 patients who underwent ophthalmologic examinations and oral examination with community periodontal index (CPI) probe. AMD was diagnosed based on criteria such as presence of soft indistinct drusen orreticular drusen and presence of hard or soft distinct drusen with pigmentary abnormalities in the absence of late AMD. Results: There were 102 males and 76 females. 61.3% (108) patients had periodontal diseases and 8.4% (15) had AMD. Among AMD patients, habit of smoking (10), hypertensive (8), anemia (12) and cardiovascular disease (5) was evident. Serum HDL level was 54.2 mg/dl, serum ferritin level was 104.6 ng/ml and BMI was 28.4 Kg/m2. AMD patients had severe periodontal diseases in 7, moderate in 3 and 2 in mild, non AMD had 1 moderate and 2 in severe periodontal diseases. The difference between AMD and non AMD was significant (P< 0.05). Conclusion: AMD patients had severe periodontal diseases as compared to non AMD patients. © This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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牙周病与黄斑变性关系的临床研究
背景:牙周病是导致牙齿脱落的主要原因。评估牙周病与黄斑变性之间的相关性。材料与方法:采用社区牙周指数(CPI)探针对178例患者进行眼科检查和口腔检查。AMD的诊断标准是,在没有晚期AMD的情况下,是否存在软质模糊结节或网状结节,是否存在硬质或软质明显结节并伴有色素异常。结果:男性102例,女性76例。61.3%(108例)有牙周病,8.4%(15例)有黄斑变性。在AMD患者中,吸烟习惯(10例)、高血压(8例)、贫血(12例)和心血管疾病(5例)较为明显。血清HDL为54.2 mg/dl,铁蛋白为104.6 ng/ml, BMI为28.4 Kg/m2。AMD患者有重度牙周病7例,中度牙周病3例,轻度牙周病2例,非AMD患者有中度牙周病1例,重度牙周病2例。AMD与非AMD差异有统计学意义(P< 0.05)。结论:与非AMD患者相比,AMD患者有严重的牙周病。©这是一篇根据知识共享署名许可(https://creativecommons.org/licenses/by/4.0/)发布的开放获取文章,该许可允许在任何媒体上不受限制地使用、分发和复制,前提是要注明原作者和来源。
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