{"title":"Calibration of a three-dimensional photodynamic therapy illumination system and its segmentation assessment for port-wine stains","authors":"Yun-qiu Feng, Xiaoming Hu, Ya Zhou, Yong Wang","doi":"10.1515/plm-2016-0014","DOIUrl":null,"url":null,"abstract":"Abstract The uniformity of light dosimetry is an important parameter that affects the efficacy of photodynamic therapy (PDT). Although this uniformity can be improved by a three-dimensional (3D) digital PDT illumination system, it has a low field-of-view (FOV) utilization rate. A checkerboard calibration method using color coding is proposed to calibrate both the projector and camera of the system with a broad common FOV. Experiments reveal that the proposed method increases the utilization rate by up to three times compared with noncolor-coding methods with almost the same accuracy. A fine distinction of phantom lesions in the 3D system can be obtained by clustering, which may be used to optimize the treatment and light-dosimetry evaluation.","PeriodicalId":20126,"journal":{"name":"Photonics & Lasers in Medicine","volume":"5 1","pages":"195 - 202"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photonics & Lasers in Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/plm-2016-0014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Abstract The uniformity of light dosimetry is an important parameter that affects the efficacy of photodynamic therapy (PDT). Although this uniformity can be improved by a three-dimensional (3D) digital PDT illumination system, it has a low field-of-view (FOV) utilization rate. A checkerboard calibration method using color coding is proposed to calibrate both the projector and camera of the system with a broad common FOV. Experiments reveal that the proposed method increases the utilization rate by up to three times compared with noncolor-coding methods with almost the same accuracy. A fine distinction of phantom lesions in the 3D system can be obtained by clustering, which may be used to optimize the treatment and light-dosimetry evaluation.
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