Association of Ambient Air Pollution with Respiratory Hospitalization in Eastern China

Yan Wang, Yi-sheng Zhang, Hong-li Li
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Abstract

In order to evaluate the effects of acute air pollution exposures on the health of respiratory system, respiratory hospital admissions data at community-based hospitals and air quality data were collected from 1st January, 2002 to 31st December, 2005 in L District of Jinan, Shandong province. On the basis of controlling for some confounding factors, such as the long-term trend of hospital admissions, 'day of the week' (DOW) effect, meteorological factor and so on, with semi-parametric generalized additive model (GAM) being employed, the regression model was established. Results showed that PM10, SO2 and NO2 were all associated with increased risk of respiratory hospital admissions. The best lag days for PM10, NO2 were current day (lag 0) and three days before (lag 3), while average moving within four days was best suitable (avg03) for SO2. The effect of a 10 mug/m3 rise in PM10 was estimated to represent a 0.38% (95% confidence interval (CI): 0.24%-0.53%) increase in respiratory hospital admissions. 1.48% (95% CI: 1.24%-1.72% ) increase for a 10 mug/m3 increase in SO2 , and 0.77% (95% CI: 0.36%-1.18%) for a 10 mug/m3 increase in NO2 were also observed. Female were more susceptible than the male to pollutant. Relative risk for PM10 and SO2 in warm seasons were larger than in cold seasons.
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中国东部地区环境空气污染与呼吸系统住院的关系
为了评价急性空气污染暴露对呼吸系统健康的影响,收集了山东省济南市L区2002年1月1日至2005年12月31日社区医院呼吸系统住院数据和空气质量数据。在控制住院长期趋势、“星期”(DOW)效应、气象因素等混杂因素的基础上,采用半参数广义加性模型(GAM)建立回归模型。结果显示,PM10、SO2和NO2均与呼吸道住院风险增加相关。PM10和NO2的最佳滞后天数为当天(滞后0)和三天前(滞后3),而SO2的平均移动时间为4天内(avg03)。据估计,PM10浓度每上升10杯/立方米,呼吸道住院人数就会增加0.38%(95%可信区间(CI): 0.24%-0.53%)。SO2浓度每增加10马克杯/立方米增加1.48% (95% CI: 1.24%-1.72%), NO2浓度每增加10马克杯/立方米增加0.77% (95% CI: 0.36%-1.18%)。女性比男性更容易受到污染物的影响。温暖季节PM10和SO2的相对危险度大于寒冷季节。
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