Comparative Study on Phytochemical Composition and In Vitro Radical Scavenging Activity of Ethanolic Extracts of Landolphia lanceolata and Nutraceutical-C24/7
{"title":"Comparative Study on Phytochemical Composition and In Vitro Radical Scavenging Activity of Ethanolic Extracts of Landolphia lanceolata and Nutraceutical-C24/7","authors":"Carole Nweze Chibuzo, A. Hauwa, A. Zubairu","doi":"10.18052/WWW.SCIPRESS.COM/IJPPE.10.36","DOIUrl":null,"url":null,"abstract":"This study investigated the phytochemical composition andin-vitroradical scavenging activity of ethanolic extracts of Nutraceutical-C24/7 andLandolphialanceolatafruit. Phytochemical screening ofLandolphialanceolatafruit extractindicated the presence of phenols, flavonoids, saponins, alkaloids, terpenoids, tannins, triterpenoids and steroids. While nutraceutical-C24/7 showed precence of with exception of saponins, terpenoids and triterpenoids. Some of the identified Phytochemicals and vitamins concentrations quantified were higher inLandolphialanceolatafruit extractthan nutraceutical-C24/7 with statistically significant difference (p<0.05) with the former having flavonoids 0.062±0.00mg/ml, phenol 0.097±0.00mg/ml, vitamin C 206±42mg/dL, vitamin B154.16±0.00mg/dL and vitamin B20.11±0.00mg/dL while, Nutraceutical-C24/7 extract had flavonoid 0.117±0.00mg/ml, phenol 0.032±0.00, vitamin C 102.24±0.00mg/dL, vitamin B123.36±0.00mg/dL, and vitamin B20.067±0.00mg/dL. The study also showed that at higher concentration, DPPH radical, ferric ion, and hydrogen peroxide the extracts radical scavenging activity increased. The study showed that the extracts scavenging activities at different concentrations had higher percentage inhibition on DPPH radical, reducing power of ferric ion capabilities and reducing composition of hydrogen peroxide indicated that ethanolic extract ofLandolphialanceolatafruits showed statistically significant different (p<0.05) when compared with ethanolic extract of Nutraceutical-C24/7. Standard vitamin C percentage inhibition for DPPH radical compared well with that ofLandolphialanceolatafruit extract at higher concentration with no statistical significant different (p>0.05).The indigenous functional foodLandolphialanceolatafruit can be concluded to be a good antioxidant that can scavenge, inhibit and quench free radicals. This suggests thatLandolphialanceolatamay be considered a good source and alternative antioxidant for developing countries like Nigeria.","PeriodicalId":14237,"journal":{"name":"International Journal of Pharmacology, Phytochemistry and Ethnomedicine","volume":"7 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmacology, Phytochemistry and Ethnomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18052/WWW.SCIPRESS.COM/IJPPE.10.36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
This study investigated the phytochemical composition andin-vitroradical scavenging activity of ethanolic extracts of Nutraceutical-C24/7 andLandolphialanceolatafruit. Phytochemical screening ofLandolphialanceolatafruit extractindicated the presence of phenols, flavonoids, saponins, alkaloids, terpenoids, tannins, triterpenoids and steroids. While nutraceutical-C24/7 showed precence of with exception of saponins, terpenoids and triterpenoids. Some of the identified Phytochemicals and vitamins concentrations quantified were higher inLandolphialanceolatafruit extractthan nutraceutical-C24/7 with statistically significant difference (p<0.05) with the former having flavonoids 0.062±0.00mg/ml, phenol 0.097±0.00mg/ml, vitamin C 206±42mg/dL, vitamin B154.16±0.00mg/dL and vitamin B20.11±0.00mg/dL while, Nutraceutical-C24/7 extract had flavonoid 0.117±0.00mg/ml, phenol 0.032±0.00, vitamin C 102.24±0.00mg/dL, vitamin B123.36±0.00mg/dL, and vitamin B20.067±0.00mg/dL. The study also showed that at higher concentration, DPPH radical, ferric ion, and hydrogen peroxide the extracts radical scavenging activity increased. The study showed that the extracts scavenging activities at different concentrations had higher percentage inhibition on DPPH radical, reducing power of ferric ion capabilities and reducing composition of hydrogen peroxide indicated that ethanolic extract ofLandolphialanceolatafruits showed statistically significant different (p<0.05) when compared with ethanolic extract of Nutraceutical-C24/7. Standard vitamin C percentage inhibition for DPPH radical compared well with that ofLandolphialanceolatafruit extract at higher concentration with no statistical significant different (p>0.05).The indigenous functional foodLandolphialanceolatafruit can be concluded to be a good antioxidant that can scavenge, inhibit and quench free radicals. This suggests thatLandolphialanceolatamay be considered a good source and alternative antioxidant for developing countries like Nigeria.