Biochemical Assessment of the Hepatic and Hematological Functions of Printing Workers

S. Ahmed, H. H. Baghdadi, Fatma Mohamady El Demerdash
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Abstract

Background: In the printing industry, volatile organic compounds main sources are the uses of organic solvents, fountain solutions and cleaning agents. Biological monitoring of exposure to toxic chemicals in the workplace is a fundamental tool to evaluate human health risks and to improve occupational safety. Aims and objectives: To investigate the effects of occupational exposure to organic solvents on some hepatic and hematological parameters among printing workers. Materials and methods: This study was conducted in local printing company with two groups; the control group included (26) male healthy volunteer donors and the second is the workers group included (26) male volunteer workers, who have been exposed to chemicals for long time (10 years). Statistical analysis was employed. Results: Hemoglobin and the red blood cell count of workers group were significantly lower than control group while, liver transaminases and lactate dehydrogenase enzymes were found significantly higher among printing workers as compare to the control group. Conclusions: This study observed that the printing workers developed biochemical alterations in hematological and the hepatic enzymes with time. However, regular follow-ups are required and further studies to get better insights into the results.
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印刷工人肝脏和血液功能的生化评价
背景:在印刷工业中,挥发性有机化合物的主要来源是使用的有机溶剂、润版液和清洗剂。对工作场所接触有毒化学品进行生物监测是评估人类健康风险和改善职业安全的基本工具。目的和目的:探讨印刷工人职业性接触有机溶剂对某些肝脏和血液学指标的影响。材料和方法:本研究在当地印刷公司进行,分为两组;对照组包括26名男性健康志愿者,第二组是工人组,包括26名长期(10年)接触化学物质的男性志愿者。采用统计学分析。结果:印刷工人血红蛋白和红细胞计数明显低于对照组,而肝脏转氨酶和乳酸脱氢酶明显高于对照组。结论:本研究观察到印刷工人血液学和肝酶随时间的变化而发生生化变化。然而,需要定期的随访和进一步的研究来更好地了解结果。
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