Human genome and philosophy: What ethical challenge will human genome studies bring to the medical practices in the 21st century?

Qiu Renzong
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引用次数: 8

Abstract

A human being or person cannot be reduced to a set of human genes, or human genome. Genetic essentialism is wrong, because as a person the entity should have self-conscious and social interaction capacity which is grown in an interpersonal relationship. Genetic determinism is wrong too, the relationship between a gene and a trait is not a linear model of causation, but rather a non-linear one. Human genome is a complexity system and functions in a complexity system of human body and a complexity of systems of natural/social environment. Genetic determinism also caused the issue of how much responsibility an agent should take for her/his action, and how much degrees of freedom will a human being have. Human genome research caused several conceptual issues. Can we call a gene ‘good’ or ‘bad’, ‘superior’ of ‘inferior’? Is a boy who is detected to have the gene of Huntington’s chorea or Alzheimer disease a patient? What should the term ‘eugenics’ mean? What do the terms such as ‘gene therapy’, ‘treatment’ and ‘enhancement’ and ‘human cloning’ mean etc.? The research of human genome and its application caused and will cause ethical issues. Can human genome research and its application be used for eugenics, or only for the treatment and prevention of diseases? Must the principle of informed consent/choice be insisted in human genome research and its application? How to protecting gene privacy and combating the discrimination on the basis of genes? How to promote the quality between persons, harmony between ethnic groups and peace between countries? How to establish a fair, just, equal and equitable relationship between developing and developed countries in regarding to human genome research and its application?

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人类基因组与哲学:人类基因组研究将给21世纪的医学实践带来什么样的伦理挑战?
一个人不能被简化为一组人类基因或人类基因组。基因本质论是错误的,因为作为一个人,实体应该具有自我意识和社会互动能力,这些能力是在人际关系中成长起来的。基因决定论也是错误的,基因和性状之间的关系不是线性因果关系,而是非线性因果关系。人类基因组是一个复杂的系统,它在一个复杂的人体系统和一个复杂的自然/社会环境系统中发挥作用。基因决定论还引发了一个问题,即代理人应该为他/她的行为承担多少责任,以及人类将拥有多少自由度。人类基因组研究引起了几个概念上的问题。我们能说一个基因是“好”还是“坏”,是“优”还是“劣”?如果一个男孩被检测出患有亨廷顿舞蹈病或阿尔茨海默病的基因,那他就是病人吗?“优生学”这个术语应该是什么意思?“基因治疗”、“治疗”、“强化”、“克隆人”等词语是什么意思?人类基因组的研究及其应用已经并将继续引发伦理问题。人类基因组研究及其应用可以用于优生学,还是仅用于疾病的治疗和预防?在人类基因组研究及其应用中,是否必须坚持知情同意/选择的原则?如何保护基因隐私,打击基于基因的歧视?如何促进人与人之间的素质、民族之间的和谐、国家之间的和平?如何在人类基因组研究和应用方面建立发展中国家与发达国家之间公平、公正、平等、公正的关系?
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