Fabrication of biodegradable films using l-lactate as a chiral material to produce circularly polarized light

IF 1 Q4 ENGINEERING, BIOMEDICAL AIMS Bioengineering Pub Date : 1900-01-01 DOI:10.3934/bioeng.2022024
Po-Yeh Lin, Chien-Ming Chen, J. Lee, Yu-Chia Cheng
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Abstract

Optical activity and its relation to molecular chirality are significant in the measurement of optical rotation or circular dichroism characteristics to determine the absolute configuration of a chiral molecule. A quarter-wave plate, which is usually made from quartz, can convert linearly polarized light into circularly polarized light. In this study, we suggest using l-lactic acid (l-LA), a chiral material, and a water-based transparent glue to produce biodegradable films. Adjusting the number of thin layers, which are deposited from the mixture of l-LA and polyvinyl alcohol, leads to different phase differences, forming l-LA films. A modified microscope system was used to observe the appearance of the l-LA wave plates. Six layers and 0.8% l-LA solution were the optimal conditions to fabricate an l-LA film. The circular polarization experiment showed that the changes in maximum and minimum light intensity were within 2% compared to the average light intensity at a specific angle of the l-LA film. The performance of the l-LA film was consistent with that of a commercial quarter-wave plate. In conclusion, circularly polarized light was successfully produced using the l-LA film. The biodegradable l-LA film has widespread application in the field of biomedicine. Featured Application: l-Lactic acid film uses biodegradable and biocompatible materials. It can produce circularly polarized light and is beneficial for application in biomedicine.
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以l-乳酸盐为手性材料制备可降解膜以产生圆偏振光
旋光性及其与分子手性的关系在测量旋光性或圆二色性以确定手性分子的绝对构型方面具有重要意义。通常由石英制成的四分之一波片可以将线偏振光转换成圆偏振光。在这项研究中,我们建议使用l-乳酸(l-LA),一种手性材料,和水基透明胶来生产可生物降解的薄膜。通过调整l-LA和聚乙烯醇混合物沉积的薄层数量,可以产生不同的相位差,从而形成l-LA薄膜。采用改进的显微镜系统观察l-LA波片的形貌。6层和0.8% l-LA溶液是制备l-LA膜的最佳条件。圆偏振实验表明,与l-LA膜特定角度下的平均光强相比,最大和最小光强的变化在2%以内。l-LA薄膜的性能与商用四分之一波片的性能一致。综上所述,利用l-LA薄膜成功制备了圆偏振光。可生物降解的l-LA膜在生物医学领域有着广泛的应用。特点用途:l-乳酸膜采用可生物降解和生物相容性材料。它可以产生圆偏振光,有利于生物医学的应用。
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来源期刊
AIMS Bioengineering
AIMS Bioengineering ENGINEERING, BIOMEDICAL-
自引率
0.00%
发文量
17
审稿时长
4 weeks
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