Principles of surgical treatment of chronic post-intubation laryngotracheal stenosis in childhood

V. Vavin, I. Nazhmudinov, T. Garashchenko, D. Polyakov, K. Magomedova
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Abstract

Introduction: Post-intubation stenosis of the larynx and trachea in childhood increases annually. This is associated with an increasing number of children with severe pathology of the upper respiratory tract, as well as children requiring artificial ventilation for other reasons. Until now there have been debatable questions about surgical tactics in children with chronic cicatricial laryngeal stenosis. Aim: The aim of this article is to evaluate the effectiveness of different tactics of surgical treatment of children with chronic cicatricial post-intubation stenosis of the larynx, depending on the state of the cartilaginous frame of the larynx. Materials and Methods: We have treated 47 children with chronic cicatricial post-intubation stenosis of the larynx. Preoperative examination included endoscopy and computed tomography of the larynx and trachea. We assessed the cartilaginous framework of the larynx and trachea that influenced the choice of surgical approach. For 20 children with intact laryngeal cartilaginous frame the method of endolaryngeal microsurgery using a CO2 laser was applied. This method allowed to form a wound surface by minimum submucosal resection scar tissue, which made it possible to cover the wound with mucosal microflaps to prevent restenosis. In the surgical treatment of extended stenoses of the middle larynx, there are prerequisites for repeated replacement of the wound with excess scar tissue, which in our observations was avoided by using endoprostheses for a period of 21 days. Despite it, with a lesion of the subglottic part of the larynx, the risk of restenosis remained quite high (5 out of 12 patients), even in the absence of data for damage to the cartilaginous frame of the larynx. In 27 cases of chronic post-intubation cicatricial stenosis of the larynx, in identifying of laryngeal cartilage framework lesion before surgery, extralaryngeal laryngotracheoplasty was performed. Laryngofissure was performed in 18 children, followed by stenting from 6 to 18 months with a T-shaped silicone stent, in 9 cases—one-stage laryngotracheoplasty using auto-cartilage grafts. The applied techniques have shown high efficiency, while the use of autografts made it possible to reduce the stages and duration of surgical treatment. Conclusion: The use of a CO2 laser in combination with balloon laryngoplasty in microsurgical treatment of chronic post-intubation stenosis of the larynx in children significantly expands surgical capabilities due to high accuracy and low level of damage of surrounding tissues.
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儿童慢性插管后喉气管狭窄的手术治疗原则
儿童插管后喉和气管狭窄逐年增加。这与越来越多患有严重上呼吸道病理的儿童以及因其他原因需要人工通气的儿童有关。到目前为止,关于儿童慢性瘢痕性喉狭窄的手术策略一直存在争议。目的:本文的目的是评估不同策略的手术治疗儿童慢性瘢痕性插管后喉狭窄的有效性,这取决于喉软骨框架的状态。材料与方法:我们治疗47例慢性瘢痕性插管后喉狭窄患儿。术前检查包括喉部和气管的内窥镜检查和计算机断层扫描。我们评估了影响手术入路选择的喉部和气管软骨框架。对20例喉软骨架完整的患儿,采用CO2激光咽内显微手术治疗。这种方法允许通过最小的粘膜下切除瘢痕组织形成创面,这使得用粘膜微瓣覆盖创面以防止再狭窄成为可能。在中喉扩张性狭窄的手术治疗中,有必要用多余的瘢痕组织反复替换伤口,在我们的观察中,使用人工人工体21天避免了这种情况。尽管如此,在喉声门下部分病变的情况下,再狭窄的风险仍然很高(12例患者中有5例),即使没有关于喉软骨框架损伤的数据。对27例慢性气管插管后瘢痕性喉狭窄患者,术前识别喉软骨框架病变,行咽外喉气管成形术。18例患儿行喉裂手术,术后6 ~ 18个月行t型硅胶支架植入术,其中9例采用自体软骨一期喉气管成形术。应用的技术已经显示出高效率,而自体移植物的使用可以减少手术治疗的阶段和持续时间。结论:CO2激光联合球囊喉成形术显微外科治疗儿童气管插管后慢性喉狭窄,准确性高,对周围组织损伤程度低,显著扩大手术能力。
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