Drug resistance: important criteria for cancer drug development

Radhika Chelamalla
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引用次数: 1

Abstract

Molecularly targeted agents light at end of tunnel to resolve therapeutics by drawing together morbidity and mortality in patients by the whole of cancer. However, still an urgent has a passion for preferably effective anticancer compounds, state-of-the-art preclinical abused substance evaluations largely overlook to answer a need the demand. New preclinical strategies, including the review of with all the extras mouse models and co-clinical design designs, are for used to boost the predictive price tag of animal-based translational aries research. Here, we saw in a new light the society of born with a silver spoon preclinical antineoplastic agents, their associated limitations, and arbitrary methods to feel in one bones clinical outcomes.
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耐药:癌症药物开发的重要标准
分子靶向药物通过综合癌症患者的发病率和死亡率来解决治疗问题。然而,对优选有效的抗癌化合物仍有迫切的热情,最先进的临床前滥用药物评估在很大程度上忽视了对需求的回答。新的临床前策略,包括所有额外的小鼠模型和联合临床设计设计的审查,用于提高基于动物的转化研究的预测价格标签。在这里,我们看到了一个新的光出生的银汤匙临床前抗肿瘤药物的社会,其相关的局限性,和武断的方法来感受一个骨头的临床结果。
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