Spindle cell myoepithelial carcinoma of the oral cavity—A report of two cases

Abstract

Myoepithelial carcinomas are not as rare as is generally believed, but they are simply not well recognized. Those arising in the oral cavity and exhibiting pure spindle cell morphology are often difficult to diagnose primarily and are likely to be misinterpreted as other more common spindle cell lesions of the oral cavity. Use of ancillary studies like Electron microscopy (EM) and immunohistochemistry (IHC) is very much essential for confirmation of diagnosis. Here we present two such cases of spindle cell myoepithelial carcinoma, which were initially misinterpreted as nerve sheath tumours after IHC and later presented with multiple recurrences and lymph node metastasis.