Oral Oncology Extra最新文献

We herein report a case of the effectiveness of 4 Gy single fraction high-dose-rate mold brachytherapy in the palliative treatment of a painful recurrent soft palate carcinoma in a previously irradiated field. A 73-year-old man with a painful recurrent squamous cell carcinoma in the right soft palate in a previously irradiated field was treated with high-dose-rate mold brachytherapy. Although only 4 Gy could be delivered, the patient showed a reduction in the degree of pain in the right soft palate after the treatment. Unfortunately, the patient died of interrecurrent disease with pleural metastases five months after the brachytherapy.

Spindle cell lipoma is a benign tumour composed of mature fat cells, spindle cells, and a myxoid matrix separated by thick bands of birefringent collagen. Oral spindle cell lipoma is a very rare lesion. We report a case of spindle cell lipoma of the cheek. A 42-year-old woman was referred to our department because of a painless swelling on the left cheek. Clinical examination revealed a mobile, well-demarcated mass of the cheek. The tumour was removed surgically under general anaesthesia. A histopathological specimen revealed a spindle cell lipoma. Following surgery, no evidence of recurrence has been observed.

Because the submandibular gland is believed to have no intraparenchymal lymph nodes, preserving the submandibular gland for neck dissection and transferring the submandibular gland in order to prevent xerostomia induced by radiation therapy in patients with head and neck cancer have recently been described. We report a case of intraparenchymal metastasis in the submandibular gland 8 months after the initial intraoral excision of tongue cancer. This finding offers evidence that the submandibular gland includes intraparenchymal metastasis that can be involved with cancer.

Desmoplastic malignant melanoma (DMM) is a distinctive variant of malignant melanoma. DMM involving the oral mucosa is very rare and to our knowledge, there are only 16 cases reported in the English literature. This is a case report of DMM in a 32-year-old male patient involving the maxillary alveolus.

A hybrid odontogenic tumour comprising three distinct lesions is extremely rare. We presented a hybrid odontogenic tumour composed of a calcifying cystic odontogenic tumour (CCOT), a solid multicystic ameloblastoma (A-S/M) and an adenomatoid odontogenic tumour (AOT). This tumour was observed in the anterior area of the mandible of a 64-year-old Chinese woman. Masses of ghost epithelial cells with the characteristics of CCOT were seen in the lining of the cyst. The odontogenic epithelia with the features of A-S/M and AOT were also observed.

Soft tissue has been recently recognized as a primary site for myoepithelial tumour and only a small number has been reported to occur in the head and neck. Although the majority of myoepithelial tumours of the soft tissue are benign, some can be aggressive and develop distant metastases.

We describe a patient with malignant myoepithelial tumour occurring in the soft tissue of the head and neck and rapid metastatic progression. In contrast to previous publications warning for overtreatment of patients with myoepithelial tumours, our report suggests that early and correct diagnosis followed by a radical therapeutic approach is required when there is evidence of malignancy.