Candida spp. associated with COVID-19 and its Susceptibility to some Antifungals

Mohammed M. Alkhuzaie, N. Jasim
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Abstract

This study aimed to conduct a survey of the Candida species associated with COVID-19 viral infection in 150 patients who were admitted to the intensive care unit (ICU) in Al-Diwaniyah Teaching Hospital in Al-Diwaniyah City, Iraq, for a five-month period from October 2021 to February 2022. The results indicated the dominance of Candida spp. over the rest of the isolated fungal species, with 97 isolates (64.66%). C. albicans was shown to be the most abundant species with a percentage of 55.67 percent (P 0.05), compared to the other Candida species that were isolated (Candida tropicalis 13.4 percent, Candida glabrata 12 percent, Candida krusie and Candida parapsilosis with 9.28 percent). In addition, we brought attention to the excellent action of the antifungals amphotericin B, itraconazole, and voriconazole, all of which have a high susceptibility rate.
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与COVID-19相关的念珠菌及其对某些抗真菌药物的敏感性
本研究旨在对伊拉克Al-Diwaniyah市Al-Diwaniyah教学医院重症监护病房(ICU)收治的150名患者中与COVID-19病毒感染相关的念珠菌物种进行调查,为期5个月,从2021年10月至2022年2月。结果表明,念珠菌属真菌以97株(64.66%)居首位。其中,白色念珠菌数量最多,占55.67% (P < 0.05),其余念珠菌分别为热带念珠菌13.4%、光秃念珠菌12%、克鲁丝念珠菌和假丝念珠菌9.28%。此外,我们注意到抗真菌药物两性霉素B、伊曲康唑和伏立康唑的良好作用,它们都有很高的敏感性。
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