Pub Date : 2023-02-15DOI: 10.29350/qjps.2022.27.1.1604
Abbas Mayar Hezam
The current study aimed to use the auxotroph's tryptophan Escherichia coli as a test to detect Ibuprofen's mutagenic potential. the Ames test was used to detect reverse mutations in auxotroph's E. coli treated with Ibuprofen. The results showed a significant increase (P< 0.05) in reverse colonies of auxotroph's E. coli treated with 250 and 500 mg/mL of Ibuprofen compared to the negative control. The polymerase chain reaction and DNA Sequencing were used to detect the reverse mutations in the try gene of the auxotroph's E. coli. The results showed the presence of the try gene in all isolates treated with 250 and 500 mg/mL of Ibuprofen at a percentage of (100%). The try gene was sequenced using BLAST software and compared to the gene sequence of a standard isolate. The genetic variation analysis of the try gene isolates treated with Ibuprofen revealed that point mutations in the DNA of the try gene altered protein translation.
{"title":"Design of a bacterial system using Escherichia coli to detect the mutagenic effect of some drugs","authors":"Abbas Mayar Hezam","doi":"10.29350/qjps.2022.27.1.1604","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1604","url":null,"abstract":"The current study aimed to use the auxotroph's tryptophan Escherichia coli as a test to detect Ibuprofen's mutagenic potential. the Ames test was used to detect reverse mutations in auxotroph's E. coli treated with Ibuprofen. The results showed a significant increase (P< 0.05) in reverse colonies of auxotroph's E. coli treated with 250 and 500 mg/mL of Ibuprofen compared to the negative control. The polymerase chain reaction and DNA Sequencing were used to detect the reverse mutations in the try gene of the auxotroph's E. coli. The results showed the presence of the try gene in all isolates treated with 250 and 500 mg/mL of Ibuprofen at a percentage of (100%). The try gene was sequenced using BLAST software and compared to the gene sequence of a standard isolate. The genetic variation analysis of the try gene isolates treated with Ibuprofen revealed that point mutations in the DNA of the try gene altered protein translation.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80354256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-15DOI: 10.29350/qjps.2021.26.5.1605
Abbas Mayar Hezam
The current study's goal was to identify virulence factors (genes) in P. mirabilis. A total of 25/100 (25%) Proteus mirabilis were obtained from patients with otitis media and identified using culture and biochemical characteristics, and Polymerase chain reaction (PCR). The PCR technique was used to detect the 16S rRNA gene and all virulence factors, including the ureC gene, which encodes urease synthesis, the flaA gene, which encodes flagella and fimbriae production, the hpmA gene, which encodes hemolysin production, and the zapA gene, which encodes protease. The results revealed that Proteus mirabilis isolates have 100% of the 16S rRNA gene, 100% of the ureC gene, 95% of the flaA gene, 95% of the hpmA gene, and 100% of the zapA gene.
{"title":"Molecular characterization of Proteus mirabilis virulence factors isolated from patients with otitis media in Diwaniyah, Iraq","authors":"Abbas Mayar Hezam","doi":"10.29350/qjps.2021.26.5.1605","DOIUrl":"https://doi.org/10.29350/qjps.2021.26.5.1605","url":null,"abstract":"The current study's goal was to identify virulence factors (genes) in P. mirabilis. A total of 25/100 (25%) Proteus mirabilis were obtained from patients with otitis media and identified using culture and biochemical characteristics, and Polymerase chain reaction (PCR). The PCR technique was used to detect the 16S rRNA gene and all virulence factors, including the ureC gene, which encodes urease synthesis, the flaA gene, which encodes flagella and fimbriae production, the hpmA gene, which encodes hemolysin production, and the zapA gene, which encodes protease. The results revealed that Proteus mirabilis isolates have 100% of the 16S rRNA gene, 100% of the ureC gene, 95% of the flaA gene, 95% of the hpmA gene, and 100% of the zapA gene.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73371381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-21DOI: 10.29350/qjps.2022.27.1.1592
Sabih Askandar, Beyda S. Abdullah, L. Khaleel
In our study we introduced soft i-open sets and soft i-star-generalized-w-closed sets in soft bi-topological spaces, , using the notion of soft i-open sets in soft-topological-space, . We besides that give examples to clarify these relationships while presenting some essential characteristics and relationships between various groups of sets. Besides that we studied the property of soft bi-topologically extended and non-soft bi-topologically extended of soft i-open sets in soft bi-topological spaces by proofs and examples.
{"title":"Soft i-Open Sets in Soft Bi-Topological Spaces","authors":"Sabih Askandar, Beyda S. Abdullah, L. Khaleel","doi":"10.29350/qjps.2022.27.1.1592","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1592","url":null,"abstract":"In our study we introduced soft i-open sets and soft i-star-generalized-w-closed sets in soft bi-topological spaces, , using the notion of soft i-open sets in soft-topological-space, . We besides that give examples to clarify these relationships while presenting some essential characteristics and relationships between various groups of sets. Besides that we studied the property of soft bi-topologically extended and non-soft bi-topologically extended of soft i-open sets in soft bi-topological spaces by proofs and examples.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73196099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-17DOI: 10.29350/qjps.2022.27.1.1512
Suhad Muhajer
Today the encryption of images has be a requirement to protect a secret image from unauthorized arrival. Different techniques have been presented and sophisticated in spatial, frequency and hybrid domains to encrypt the image securely. Depending on on the security requirements, encryption methods can be classified as full encryption or partial encryption. This paper proposes a review of several image encryption methods based on AES and DES. The results of previous research have shown that good results in many security analysis such as time execution, entropy, differential attacks, histogram and others. Comparison between AES and DES based on number of factors are presented in this work.
{"title":"S A Review of DES and AES algorithms for image Encryption","authors":"Suhad Muhajer","doi":"10.29350/qjps.2022.27.1.1512","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1512","url":null,"abstract":" Today the encryption of images has be a requirement to protect a secret image from unauthorized arrival. Different techniques have been presented and sophisticated in spatial, frequency and hybrid domains to encrypt the image securely. Depending on on the security requirements, encryption methods can be classified as full encryption or partial encryption. This paper proposes a review of several image encryption methods based on AES and DES. The results of previous research have shown that good results in many security analysis such as time execution, entropy, differential attacks, histogram and others. Comparison between AES and DES based on number of factors are presented in this work.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85278500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-18DOI: 10.29350/qjps.2022.27.1.1542
H. G. Abdulshaheed
Obesity is rapidly becoming a health problem, and it is considered a metabolic disease of epidemic proportions. Obesity is also associated with many comorbidities such as hyperlipidemia, fatty liver, atherosclerosis, cancer. Use of over-the-counter weight-loss supplements has become more common in the world; Xenical and Lipo-6 are two examples of nutritional supplements that do not pass safety research before being sold to the consumer. The ability of Xenical and lipo-6 supplements on DNA fragmentation in human lymphocytes was studied, where these cells represent important defense line of the body. On other hand, thirty white rabbits Iraqis in this experiment, weighing 2.5 to 3.0 kg were employed, which divided randomly to the three group (A: Control group, B: Xenical group, C: Lipo-6 group). In the end of experiment, all animals synthesized for collection blood to complete blood count examination and then all animal scarified for taking tissues samples to histopathological examination. The results showed that, the effects of two different types of medications on DNA fragmentation in human lymphocytes were examined. Xenical, at high concentrations (500 µg/ml), caused a significant fragmentation of lymphocytes' DNA (p ≥ 0.05); DNA fragmentation percentages were 68.5 percent after 24 hours and reached 76.4 percent after 48 hours. the lipo-6 at high concentration displayed apoptotic activity against healthy cells after 24 hours of exposure; DNA fragmentation was 80.13%. After 48 hours, the proportion of DNA fragmentation increased to 89.71 percent. As well as, the present study were conducting to determine toxicity of drug in rabbits in order to scientific information about its safety. The results of this study, reveals a histological sections for (liver, lung, heart, spleen, and intestine) in rabbits groups treated with Xenical and Lipo- 6 two capsule per day. pathological alterations in the treated rabbits' intestines, including macrophage and lymphocyte infiltration indicating chronic inflammation, furthermore, intestine section showed Macro vesicular fatty change. The spleen histological Samples founded with highly-blood foci (bleeding), highly infiltration with lymphocytes, also section exhibit highly proliferative cells with abnormal blood collections in both groups treated with Xenical and Lipo-6,in comparative to normal spleen. the lung tissue inflammation, the production of air vacuoles, damage to the alveolar sac and found a significant RBC cast in the heart muscle.
{"title":"Comparative physiology study of side effect between Xenical and Lipo-6 Supplements which treated obese rabbets","authors":"H. G. Abdulshaheed","doi":"10.29350/qjps.2022.27.1.1542","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1542","url":null,"abstract":"Obesity is rapidly becoming a health problem, and it is considered a metabolic disease of epidemic proportions. Obesity is also associated with many comorbidities such as hyperlipidemia, fatty liver, atherosclerosis, cancer. Use of over-the-counter weight-loss supplements has become more common in the world; Xenical and Lipo-6 are two examples of nutritional supplements that do not pass safety research before being sold to the consumer. \u0000The ability of Xenical and lipo-6 supplements on DNA fragmentation in human lymphocytes was studied, where these cells represent important defense line of the body. On other hand, thirty white rabbits Iraqis in this experiment, weighing 2.5 to 3.0 kg were employed, which divided randomly to the three group (A: Control group, B: Xenical group, C: Lipo-6 group). In the end of experiment, all animals synthesized for collection blood to complete blood count examination and then all animal scarified for taking tissues samples to histopathological examination. \u0000The results showed that, the effects of two different types of medications on DNA fragmentation in human lymphocytes were examined. Xenical, at high concentrations (500 µg/ml), caused a significant fragmentation of lymphocytes' DNA (p ≥ 0.05); DNA fragmentation percentages were 68.5 percent after 24 hours and reached 76.4 percent after 48 hours. the lipo-6 at high concentration displayed apoptotic activity against healthy cells after 24 hours of exposure; DNA fragmentation was 80.13%. After 48 hours, the proportion of DNA fragmentation increased to 89.71 percent. As well as, the present study were conducting to determine toxicity of drug in rabbits in order to scientific information about its safety. The results of this study, reveals a histological sections for (liver, lung, heart, spleen, and intestine) in rabbits groups treated with Xenical and Lipo- 6 two capsule per day. pathological alterations in the treated rabbits' intestines, including macrophage and lymphocyte infiltration indicating chronic inflammation, furthermore, intestine section showed Macro vesicular fatty change. The spleen histological Samples founded with highly-blood foci (bleeding), highly infiltration with lymphocytes, also section exhibit highly proliferative cells with abnormal blood collections in both groups treated with Xenical and Lipo-6,in comparative to normal spleen. the lung tissue inflammation, the production of air vacuoles, damage to the alveolar sac and found a significant RBC cast in the heart muscle.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74609532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-08DOI: 10.29350/qjps.2022.27.1.1517
Mohammed M. Alkhuzaie, N. Jasim
This study aimed to conduct a survey of the Candida species associated with COVID-19 viral infection in 150 patients who were admitted to the intensive care unit (ICU) in Al-Diwaniyah Teaching Hospital in Al-Diwaniyah City, Iraq, for a five-month period from October 2021 to February 2022. The results indicated the dominance of Candida spp. over the rest of the isolated fungal species, with 97 isolates (64.66%). C. albicans was shown to be the most abundant species with a percentage of 55.67 percent (P 0.05), compared to the other Candida species that were isolated (Candida tropicalis 13.4 percent, Candida glabrata 12 percent, Candida krusie and Candida parapsilosis with 9.28 percent). In addition, we brought attention to the excellent action of the antifungals amphotericin B, itraconazole, and voriconazole, all of which have a high susceptibility rate.
{"title":"Candida spp. associated with COVID-19 and its Susceptibility to some Antifungals","authors":"Mohammed M. Alkhuzaie, N. Jasim","doi":"10.29350/qjps.2022.27.1.1517","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1517","url":null,"abstract":"This study aimed to conduct a survey of the Candida species associated with COVID-19 viral infection in 150 patients who were admitted to the intensive care unit (ICU) in Al-Diwaniyah Teaching Hospital in Al-Diwaniyah City, Iraq, for a five-month period from October 2021 to February 2022. The results indicated the dominance of Candida spp. over the rest of the isolated fungal species, with 97 isolates (64.66%). C. albicans was shown to be the most abundant species with a percentage of 55.67 percent (P 0.05), compared to the other Candida species that were isolated (Candida tropicalis 13.4 percent, Candida glabrata 12 percent, Candida krusie and Candida parapsilosis with 9.28 percent). In addition, we brought attention to the excellent action of the antifungals amphotericin B, itraconazole, and voriconazole, all of which have a high susceptibility rate.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82429825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-29DOI: 10.29350/qjps.2022.27.1.1533
Abtisam Jasim Abbas
The current study was concerned with investigating parasitic infections in Barbus Xanthopterus fish in Al-Diwaniyah River, for the period (July 2020-December 2020). (218) fish were collected from three different locations along the Al-Diwaniyah River. The results of the laboratory examination indicated that the fish were infected with the parasite Chilodonella Cyprinid and Eimiria sinenis. The current study recorded changes in the physical and chemical properties of Al-Diwaniyah River water, as the water temperature values, measured turbidity values, pH, electrical conductivity, hardness and TDS recorded a clear variation during the months of the study. The results of the statistical analysis indicated that there were significant differences between these variables at a level of probability (P≤0.05).
{"title":"Environmental and diagnostic study of some parasites in Barbus Xanthopterus fish of Al-Diwaniyah River","authors":"Abtisam Jasim Abbas","doi":"10.29350/qjps.2022.27.1.1533","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1533","url":null,"abstract":" The current study was concerned with investigating parasitic infections in Barbus Xanthopterus fish in Al-Diwaniyah River, for the period (July 2020-December 2020). (218) fish were collected from three different locations along the Al-Diwaniyah River. The results of the laboratory examination indicated that the fish were infected with the parasite Chilodonella Cyprinid and Eimiria sinenis. The current study recorded changes in the physical and chemical properties of Al-Diwaniyah River water, as the water temperature values, measured turbidity values, pH, electrical conductivity, hardness and TDS recorded a clear variation during the months of the study. The results of the statistical analysis indicated that there were significant differences between these variables at a level of probability (P≤0.05).","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89921146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-17DOI: 10.29350/qjps.2022.27.1.1528
H. Jaber, S. Fazaa, Almiyah
The current study have been included 250 samples diabetic foot ulcer patients attending in Al-Diwaniyah Teaching Hospital and private clinics at a period of study from beginning October 2021 to February 2022, Isolates were identified by morphological form on blood agar and macConkey agar, traditional biochemical tests and then confirmed by Vitek 2 system.
{"title":"Antibiotic susceptibility of Proteus Mirabillis that isolates of Diabetic foot ulcers in Al- Diwaniyah Hospital","authors":"H. Jaber, S. Fazaa, Almiyah","doi":"10.29350/qjps.2022.27.1.1528","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.1.1528","url":null,"abstract":"The current study have been included 250 samples diabetic foot ulcer patients attending in Al-Diwaniyah Teaching Hospital and private clinics at a period of study from beginning October 2021 to February 2022, Isolates were identified by morphological form on blood agar and macConkey agar, traditional biochemical tests and then confirmed by Vitek 2 system.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77406690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-06DOI: 10.29350/qjps.2022.27.2.1473
Mohamةed Altaie
Photonic crystal fibers in the late period occupied a wide range of studies and research because of the ease of dealing with them in terms of design and installation, as there is a group of parameters used in them that can affect the refractive index of the pulse propagation through it, including the diameter of the air holes, the distance between the air holes and their number, as this study showed in addition to the aforementioned parameters The effect of temperature on the refractive index was also studied. It has been observed that with an increase in the diameter of the air holes, the refractive index increases and, conversely, the increase in the distance between them leads to a decrease in the refractive index. As for the number of air holes, it has no clear effect. As for the temperature, which is proportional to the frequency and intensity, this increase in temperature leads to an increase in the refractive index of the pulse passing through the photonic crystal fiber. Changing the temperature of the photonic crystal fiber is an interesting for dynamics fine refractive index tuning in active refractive index shift compensation system. this paper present a numerical analysis on the effect of photonic crystal fiber temperature on refractive index and modal features. the research depend on regular hexagonal crystal lattice fibers with specific geometric parameters using finite element method.
{"title":"The Refractive Index Of Photonic Crystal Fibers As A Function Of Some Parameters And Temperature","authors":"Mohamةed Altaie","doi":"10.29350/qjps.2022.27.2.1473","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.2.1473","url":null,"abstract":"Photonic crystal fibers in the late period occupied a wide range of studies and research because of the ease of dealing with them in terms of design and installation, as there is a group of parameters used in them that can affect the refractive index of the pulse propagation through it, including the diameter of the air holes, the distance between the air holes and their number, as this study showed in addition to the aforementioned parameters The effect of temperature on the refractive index was also studied. It has been observed that with an increase in the diameter of the air holes, the refractive index increases and, conversely, the increase in the distance between them leads to a decrease in the refractive index. As for the number of air holes, it has no clear effect. As for the temperature, which is proportional to the frequency and intensity, this increase in temperature leads to an increase in the refractive index of the pulse passing through the photonic crystal fiber. Changing the temperature of the photonic crystal fiber is an interesting for dynamics fine refractive index tuning in active refractive index shift compensation system. this paper present a numerical analysis on the effect of photonic crystal fiber temperature on refractive index and modal features. the research depend on regular hexagonal crystal lattice fibers with specific geometric parameters using finite element method.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88219114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-23DOI: 10.29350/qjps.2022.27.2.1493
Helal Muhammed, b-Zeyan Abdullah
The serum levels of trace elements alterations have been linked with Type 2 Diabetes mellitus (T2 DM) and its complication. The Objectives of this study is to detect the correlation relation between serum Chromium, Magnesium (Mg), Zinc (Zn), Copper (Cu), and Iron (Fe) with Fasting Blood Sugar (FBS) in patients with type two diabetes mellitus, also to study the comparison of Ferroxidase, Transferrin, and Total iron binding capacity in patients with type two diabetes mellitus with control groups. A total of forty subjects were included in this study, they were divided in two groups (control and diabetic patients). Fasting blood samples were taken from all participants and analyzed for levels of Cr, Mg, Zn, Cu, and Fe. The concentration of serum trace elements of each sample was determined by using Inductively Coupled Plasma Optical Emission Spectroscopy. A negative correlation was found between Mg, Zn, and Fe level in Type-2 diabetics with FBS, whereas serum copper level shows significant positive correlation with FBS, and chromium shown no significant correlation with FBS. Ferroxidase, and Total binding capacity showed a significant increase, while a significant decrease was found in Transferrin of T2DM.
{"title":"Correlation and comparison of some trace elements and their related proteins in Type 2 Diabetes mellitus in Kalars city/ Kurdistan-Iraq.","authors":"Helal Muhammed, b-Zeyan Abdullah","doi":"10.29350/qjps.2022.27.2.1493","DOIUrl":"https://doi.org/10.29350/qjps.2022.27.2.1493","url":null,"abstract":"The serum levels of trace elements alterations have been linked with Type 2 Diabetes mellitus (T2 DM) and its complication. The Objectives of this study is to detect the correlation relation between serum Chromium, Magnesium (Mg), Zinc (Zn), Copper (Cu), and Iron (Fe) with Fasting Blood Sugar (FBS) in patients with type two diabetes mellitus, also to study the comparison of Ferroxidase, Transferrin, and Total iron binding capacity in patients with type two diabetes mellitus with control groups. A total of forty subjects were included in this study, they were divided in two groups (control and diabetic patients). Fasting blood samples were taken from all participants and analyzed for levels of Cr, Mg, Zn, Cu, and Fe. The concentration of serum trace elements of each sample was determined by using Inductively Coupled Plasma Optical Emission Spectroscopy. A negative correlation was found between Mg, Zn, and Fe level in Type-2 diabetics with FBS, whereas serum copper level shows significant positive correlation with FBS, and chromium shown no significant correlation with FBS. Ferroxidase, and Total binding capacity showed a significant increase, while a significant decrease was found in Transferrin of T2DM.","PeriodicalId":7856,"journal":{"name":"Al-Qadisiyah Journal Of Pure Science","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73295768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}