{"title":"Solubilization of Hydroxypropyl-β-Cyclodextrin on Cholesterol in Aqueous Solution","authors":"C. Zou, Lu Zhou, Ya-li Wang, Lu Li","doi":"10.6000/1929-5030.2014.03.02.1","DOIUrl":null,"url":null,"abstract":"Hydroxypropyl-I²-Cyclodextrin (HP-I²-CD), prepared via reaction of I²-Cyclodextrin (I²-CD) and propylene oxide (PO), is utilized to research solubilization of HP-I²-CD on cholesterol in aqueous solution. HP-I²-CD is characterized by Fourier Transform Infrared Spectrometry (FT-IR), and concentrations of cholesterol solution are measured by ultraviolet and visible (UV VIS) spectrophotometer. The research on optimal synthesis conditions of HP-I²-CD indicates that sodium hydroxide amounts have the most effect on yields of product. The maximum solubilization multiples of HP-I²-CD reaches 15, below which molecular rate of HP-I²-CD and cholesterol in inclusion complex is 1:1.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"32 1","pages":"48-52"},"PeriodicalIF":0.0000,"publicationDate":"2014-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Solution Chemistry and Modeling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6000/1929-5030.2014.03.02.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hydroxypropyl-I²-Cyclodextrin (HP-I²-CD), prepared via reaction of I²-Cyclodextrin (I²-CD) and propylene oxide (PO), is utilized to research solubilization of HP-I²-CD on cholesterol in aqueous solution. HP-I²-CD is characterized by Fourier Transform Infrared Spectrometry (FT-IR), and concentrations of cholesterol solution are measured by ultraviolet and visible (UV VIS) spectrophotometer. The research on optimal synthesis conditions of HP-I²-CD indicates that sodium hydroxide amounts have the most effect on yields of product. The maximum solubilization multiples of HP-I²-CD reaches 15, below which molecular rate of HP-I²-CD and cholesterol in inclusion complex is 1:1.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
