Pharmaceutical forms and Drug-disease Interaction: An Old-new Case

N. Al-Somai
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Abstract

Theophylline is a drug that has been used for asthma disease, for more than 80 years. It has been used for its bronchodilator effects; however, dosing was critical because of it is narrow therapeutic index which may lead to failure in treatment of toxicity. This case illustrates the important of individualization of the theophylline based on the patient medical history. Pharmacist intervention and knowledge in the drug disease interaction, considering the pharmacokinetics data, would be valuable for the success of the treatment
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药物形态与药物-疾病相互作用:一个新旧案例
茶碱是一种用于治疗哮喘的药物,已有80多年的历史。它被用于支气管扩张作用;然而,剂量是至关重要的,因为它是狭窄的治疗指标,可能导致治疗失败的毒性。这个病例说明了基于病人病史的茶碱个体化治疗的重要性。考虑到药代动力学数据,药剂师的干预和药物疾病相互作用的知识对治疗的成功是有价值的
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