A Case Report of Fibrolamellar Hepatocellular Carcinoma in a Young Adult

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Annals of King Edward Medical University Lahore Pakistan Pub Date : 2022-08-04 DOI:10.21649/akemu.v28i2.5095
M. Atiq, M. Haroon, Muhammad Imran Khan, A. Ammar, Wardah Khalid, F. Hanif
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Abstract

Among the four histopathological variants of hepatocellular carcinoma, Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare variant of hepatocellular carcinoma (HCC). It occurs in less than 1 % cases of hepatocellular carcinoma with distinct features as compared to classical HCC. It differs from typical HCC in terms of epidemiology, etiology, clinical presentation and prognosis. In this case report we are going to present a case of fibrolamellar variety of HCC in a 20-year young male with no history of previous liver disease and no characteristics features on Computed Tomography (CT) scan when compared with typical HCC. After discussing in multidisciplinary meeting, he underwent non anatomical liver resection which remained uneventful. Histopathology of the biopsy sample revealed FLHCC. No neoadjuvant therapy was given. Patient was kept on 1 year follow-up and no recurrence or metastasis occurred.
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青壮年纤维层状肝细胞癌1例报告
在肝细胞癌的四种组织病理学变异中,纤维层状肝细胞癌(FLHCC)是一种罕见的肝细胞癌(HCC)变异。它发生在少于1%的肝细胞癌病例中,与经典HCC相比具有明显的特征。它在流行病学、病因学、临床表现和预后方面与典型HCC不同。在本病例报告中,我们将报告一例20岁年轻男性的纤维板层型HCC,与典型HCC相比,他没有既往肝脏疾病史,计算机断层扫描(CT)扫描没有特征。在多学科会议上讨论后,他接受了非解剖性肝切除术,手术顺利。活检样本的组织病理学显示为FLHCC。未给予新辅助治疗。患者随访1年,未发生复发和转移。
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发文量
75
审稿时长
12 weeks
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